Evidence map›Paper›PMID 41718046›Full record

ArticleEpidemiologia (Basel, Switzerland)2026

Trends and Determinants of Dementia-Related Mortality in Mexico, 2017-2023.

Dennis M Lopez-Samayoa, Angel M Campos-Sosa, Paola Asuncion Bojorquez-Chan, Sara E Martinez-Medel, Jorge C Guillermo-Herrera, Edgar Villarreal-Jimenez, Reinhard Janssen-Aguilar, Cristina Rodriguez Peres-Mitre, Nina Mendez-Dominguez

Abstract read
In one paragraph

Article in Epidemiologia (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dennis M Lopez-SamayoaSchool of Medicine, Universidad Autonoma de Durango, Durango 34200, Mexico.ORCID 0009-0000-4376-7947
Angel M Campos-SosaSchool of Medicine, Universidad Marista de Merida, Merida 97302, Mexico.ORCID 0009-0005-1282-9136
Paola Asuncion Bojorquez-ChanCentro Educativo Rodríguez Tamayo, Cd. Caucel, Merida 97314, Mexico.ORCID 0009-0003-4231-2707
Sara E Martinez-MedelHospital Regional de Alta Especialidad de la Peninsula de Yucatan, Servicios de Salud del Instituto Mexicano del Seguro Social, IMSS-BIENESTAR, Merida 97130, Mexico.
Jorge C Guillermo-HerreraHospital Regional de Alta Especialidad de la Peninsula de Yucatan, Servicios de Salud del Instituto Mexicano del Seguro Social, IMSS-BIENESTAR, Merida 97130, Mexico.
Edgar Villarreal-JimenezCentro Educativo Rodríguez Tamayo, Cd. Caucel, Merida 97314, Mexico.ORCID 0000-0002-4258-4409
Reinhard Janssen-AguilarInterventional Psychiatry Program, St. Michael's Hospital, Toronto, ON M5B 1W8, Canada.
Cristina Rodriguez Peres-MitreHospital Regional de Alta Especialidad de la Peninsula de Yucatan, Servicios de Salud del Instituto Mexicano del Seguro Social, IMSS-BIENESTAR, Merida 97130, Mexico.
Nina Mendez-DominguezHospital Regional de Alta Especialidad de la Peninsula de Yucatan, Servicios de Salud del Instituto Mexicano del Seguro Social, IMSS-BIENESTAR, Merida 97130, Mexico.ORCID 0000-0002-0230-0731

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDementia is an increasing public health challenge in Mexico, yet recent national data on mortality patterns remain limited. This study examines temporal trends in dementia-related mortality and its sociodemographic and ecological characteristics among adults aged ≥65 years from 2017 to 2023.

methodsNational mortality records from the General Directorate of Health Information were analyzed. Annual dementia-related mortality rates were calculated based on mid-year population estimates from CONAPO. Trends were assessed with regression analysis, including population offsets, and individual- and state-level characteristics were evaluated.

resultsBetween 2017 and 2023, dementia-related deaths increased from 761 to 1425, corresponding to an observed rise from 7.9 to 14.6 deaths per 100,000 inhabitants aged ≥65 years. Period trend indicated an average annual expected increase of 18.6% in dementia related mortality. A transient decline occurred in 2020-2021, coinciding with the COVID-19 pandemic. At the individual level, higher education was associated with greater odds of dementia certification, whereas Indigenous ethnicity appeared protective, which may reflect patterns consistent with diagnostic and reporting disparities. Higher state-level life expectancy correlated with higher dementia mortality, while greater population aging was inversely associated.

conclusionsDementia-related mortality in Mexico shows a sustained upward trend with regional heterogeneity and apparent inequities in diagnosis and reporting. Strengthening mortality surveillance, improving certification quality, and integrating dementia indicators into national non-communicable disease registries are essential to guide equitable policy responses.

Indexed as

agingdementiaecological analysishealth disparitiesMexicomortality

Identifiers

PMID41718046
PMCPMC12921824

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.