Evidence map›Paper›PMID 41717949›Full record

ArticleJournal of the American Heart Association2026

Cold Waves and Elevation Strengthen the Association of Particulate Matter Exposure With Hypertension Prevalence: A Large Multiregional Study in China.

Ce Liu, Li He, Li Liu, Huanhuan Wei, Hao Zhao, Zhaoru Yang, Huan Chen, Chongjian Wang, Bin Luo

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Combined effects of apparent low temperature and PMFrontiers in public health · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ce Liu *School of Public Health, Institute of Occupational Health and Environmental Health Lanzhou University Lanzhou People's Republic of China.ORCID 0000-0003-2227-4363
Li He *School of Public Health, Institute of Occupational Health and Environmental Health Lanzhou University Lanzhou People's Republic of China.
Li Liu *Department of General Medicine, The Ninth Medical Center Chinese PLA General Hospital Beijing People's Republic of China.
Huanhuan WeiSchool of Public Health, Institute of Occupational Health and Environmental Health Lanzhou University Lanzhou People's Republic of China.
Hao ZhaoSchool of Public Health, Institute of Occupational Health and Environmental Health Lanzhou University Lanzhou People's Republic of China.
Zhaoru YangSchool of Public Health, Institute of Occupational Health and Environmental Health Lanzhou University Lanzhou People's Republic of China.
Huan ChenSchool of Public Health, Institute of Occupational Health and Environmental Health Lanzhou University Lanzhou People's Republic of China.
Chongjian WangDepartment of Epidemiology and Health Statistics, College of Public Health Zhengzhou University Zhengzhou People's Republic of China.ORCID 0000-0001-5091-6621
Bin LuoSchool of Public Health, Institute of Occupational Health and Environmental Health Lanzhou University Lanzhou People's Republic of China.ORCID 0000-0001-9324-8942

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypertension is a major global health burden. While air pollution is a known risk factor, the interactive effects of co-occurring stressors like cold weather and geographic elevation are poorly understood. This study investigated the independent and joint effects of long-term particulate matter (PM) exposure, cold waves, and elevation on hypertension.

methodsWe conducted a cross-sectional study of 27 602 adults across multiple regions in China. Long-term exposures to PM and its chemical components were estimated using 3 independent, high-resolution data sets, alongside cumulative cold-wave days and residential elevation. Generalized linear models and principal component analysis were used to estimate associations with hypertension prevalence and blood pressure, assessing both multiplicative and additive interactions.

resultsLong-term exposure to PM with a diameter of ≤2.5 μm was significantly associated with higher odds of hypertension (odds ratio per 10 μg/m

conclusionsThe association between air pollution and hypertension is significantly modified by local climatic and geographic conditions. The synergistic effect of PM and cold waves suggests current assessments may underestimate the burden in susceptible regions, necessitating integrated, climate-informed public health strategies.

Indexed as

Air PollutantsAir PollutionBlood PressureCold TemperatureEnvironmental ExposureHypertensionParticulate MatterAdultChinaCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceRisk FactorsAir PollutantsParticulate Mattercold waveelevationhypertensionparticulate mattersynergistic effect

Identifiers

PMID41717949
PMCPMC13055748

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.