Evidence map›Paper›PMID 41717943›Full record

Trial reportThoracic cancer2026

High-Flow Nasal Cannula Versus Conventional Oxygen Therapy in Patients Undergoing Thoracic Surgery: A Randomized Controlled Trial.

Desire T Maioli, Louise M Corbellini, Cintia L Santos, Clovis T Bevilacqua Filho, Cristiano F Andrade, Andre P Schmidt

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Thoracic cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Desire T MaioliPrograma de Pós-graduação em Ciências Pneumológicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.ORCID https://orcid.org/0009-0005-5040-0840
Louise M CorbelliniClinica de Anestesiologia e Tratamento da Dor Bento Gonçalves, Hospital Tacchini, Bento Gonçalves, Rio Grande do Sul, Brazil.ORCID https://orcid.org/0000-0003-4935-4275
Cintia L SantosClinica de Anestesiologia e Tratamento da Dor Bento Gonçalves, Hospital Tacchini, Bento Gonçalves, Rio Grande do Sul, Brazil.ORCID https://orcid.org/0000-0001-7331-7330
Clovis T Bevilacqua FilhoPrograma de Pós-graduação em Ciências Pneumológicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.ORCID https://orcid.org/0000-0002-1375-7489
Cristiano F AndradePrograma de Pós-graduação em Ciências Pneumológicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.ORCID https://orcid.org/0000-0002-6431-3079
Andre P SchmidtPrograma de Pós-graduação em Ciências Pneumológicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.ORCID https://orcid.org/0000-0001-5425-2180

Funding

Tacchini Hospital
6 · The paper itself

Abstract

BACKGROUND AND

objectivePostoperative pulmonary complications (PPC) are linked to higher morbidity and healthcare costs. High-flow nasal cannula (HFNC) oxygen therapy may mitigate PPC by enhancing oxygenation and easing respiratory effort. This study assessed HFNC's efficacy versus conventional oxygen therapy in reducing PPC during anesthetic induction and extubation in elective thoracic surgery for lung resection.

methodsIn a single-center randomized clinical trial, 90 patients undergoing elective thoracic surgery were randomized (1:1) to HFNC or conventional oxygen therapy during induction and extubation. The primary outcome was in-hospital PPC incidence within 30 days. Secondary outcomes included intubation hypoxemia, 30-day mortality, and ICU admission. Poisson regression identified PPC predictors.

resultsPPC rates were 20.0% in the HFNC group and 26.7% in controls (relative risk [RR] 0.75, 95% CI 0.35-1.60, p = 0.455), with no significant difference. Poisson regression revealed independent predictors: chronic obstructive pulmonary disease, preoperative SpO

conclusionHFNC, applied during intubation and extubation, did not significantly reduce the incidence of PPC or secondary outcomes compared to conventional oxygen therapy in patients undergoing elective thoracic surgery. Further research is needed to explore HFNC's potential in high-risk populations or with optimized protocols, such as extended application periods or varied flow rates, to enhance perioperative respiratory management.

Indexed as

CannulaOxygen Inhalation TherapyPostoperative ComplicationsThoracic Surgical ProceduresAgedFemaleHumansMaleMiddle Agedhigh‐flow nasal cannulaoxygen inhalation therapypostoperative complicationsrandomized controlled trialsthoracic surgery

Identifiers

PMID41717943
PMCPMC12921714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.