Evidence map›Paper›PMID 41717941›Full record

ArticleJournal of the American Heart Association2026

Insomnia and Incident Cardiovascular Disease in US Hispanic/Latino Adults: Results From HCHS/SOL.

Wenqi Lü, Yongming Wang, Shuyao Wu, Meiou Wang, Jiaxue Huang, Xiangdong Tang, Ye Zhang, Rong Ren

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenqi LüSleep Medicine Center, Mental Health Center, National Center for Mental Disorders, West China Hospital Sichuan University Chengdu China.ORCID 0000-0003-4083-8257
Yongming WangSleep Medicine Center, Mental Health Center, National Center for Mental Disorders, West China Hospital Sichuan University Chengdu China.
Shuyao WuSleep Medicine Center, Mental Health Center, National Center for Mental Disorders, West China Hospital Sichuan University Chengdu China.
Meiou WangSleep Medicine Center, Mental Health Center, National Center for Mental Disorders, West China Hospital Sichuan University Chengdu China.
Jiaxue HuangSleep Medicine Center, Mental Health Center, National Center for Mental Disorders, West China Hospital Sichuan University Chengdu China.ORCID 0009-0001-8965-4347
Xiangdong TangSleep Medicine Center, Mental Health Center, National Center for Mental Disorders, West China Hospital Sichuan University Chengdu China.ORCID 0000-0001-6876-3328
Ye ZhangSleep Medicine Center, Mental Health Center, National Center for Mental Disorders, West China Hospital Sichuan University Chengdu China.
Rong RenSleep Medicine Center, Mental Health Center, National Center for Mental Disorders, West China Hospital Sichuan University Chengdu China.ORCID 0000-0002-7126-3911

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInsomnia has been recognized as an independent cardiovascular risk factor, but longitudinal evidence remains limited.

methodsWe analyzed data from 3635 participants in the HCHS/SOL (Hispanic Community Health Study/Study of Latinos). Insomnia was assessed at baseline using the Women's Health Initiative Insomnia Rating Scale and evaluated by insomnia group status, symptom severity, specific symptom dimensions, and sleep duration. The primary outcome was incident cardiovascular disease (CVD) over a median follow-up of 6.05 years, defined using Framingham composite criteria. Cox proportional hazards models were used to estimate adjusted hazard ratio (HR) and 95% CI. Subgroup and interaction analyses examined effect modification by age and sex.

resultsInsomnia was independently associated with a 78% increased risk of incident CVD (HR, 1.78 [95% CI, 1.02-3.12],

conclusionsThis study first demonstrates a prospective link between insomnia and incident CVD in a large cohort of US Hispanic/Latino adults. Baseline insomnia conferred an increased risk of developing CVD, particularly among men and younger adults. Early morning awakening drove most of this association, underscoring the need for targeted sleep interventions in this population.

Indexed as

Cardiovascular DiseasesHispanic or LatinoSleep Initiation and Maintenance DisordersAdultAgedAge FactorsFemaleHeart Disease Risk FactorsHumansIncidenceMaleMiddle AgedProportional Hazards ModelsProspective StudiesRisk AssessmentRisk Factorscardiovascular diseasecohort studyinsomniaUS Hispanic/Latino

Identifiers

PMID41717941
PMCPMC13055718

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.