Evidence map›Paper›PMID 41717677›Full record

Trial reportHypertension (Dallas, Tex. : 1979)2026

mHealth Intervention to Improve Hypertension Care in High-Risk Patients.

Kamakshi Lakshminarayan, Thomas A Murray, Scott Lunos, Teresa McCarthy, Susan A Everson-Rose, Valerie Overton, Paul E Drawz, Christopher Streib, Boonsub Sakboonyarat, Hilary Hatch and 4 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Hypertension (Dallas, Tex. : 1979), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03612271 (mGlide RCT), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03612271 naactive not recruitingnot on this map

mGlide RCT: A Clinical Glide Path To Close the Guideline-to-Practice Gap In HTN Management

TypeinterventionalSponsorUniversity of MinnesotaRan2019 to 2028Enrolled395ConditionsHypertensionArmsmGlide
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kamakshi LakshminarayanDivision of Epidemiology and Community Health (K.L., B.S., R.V.L.), School of Public Health, University of Minnesota, Minneapolis.ORCID 0000-0002-8564-8986
Thomas A MurrayDivision of Biostatistics and Health Data Science (T.A.M., J.C.), School of Public Health, University of Minnesota, Minneapolis.ORCID 0000-0003-2769-4957
Scott LunosBiostatistical Design and Analysis Center, Clinical and Translational Science Institute, University of Minnesota, Minneapolis. (S.L.).ORCID 0009-0001-0663-4624
Teresa McCarthyDepartment of Family Medicine and Community Health (T.M.C.), Medical School, University of Minnesota, Minneapolis.ORCID 0000-0002-1184-3287
Susan A Everson-RoseDepartment of Medicine and Program in Health Disparities Research, Medical School, University of Minnesota, Minneapolis (S.A.E.-R.).ORCID 0000-0002-9839-2537
Valerie OvertonFairview Health Services, Minneapolis, MN (V.O.).ORCID 0000-0003-4580-7900
Paul E DrawzDivision of Renal Diseases and Hypertension (P.E.D.), Medical School, University of Minnesota, Minneapolis.ORCID 0000-0001-7301-9253
Christopher StreibDepartment of Neurology (C.S.), Medical School, University of Minnesota, Minneapolis.ORCID 0000-0002-1119-757X
Boonsub SakboonyaratDivision of Epidemiology and Community Health (K.L., B.S., R.V.L.), School of Public Health, University of Minnesota, Minneapolis.ORCID 0000-0003-0577-0699
Hilary HatchPhreesia, New York, NY (H.H.).
Judith H HibbardInstitute for Policy Research and Innovation, University of Oregon, Eugene (J.H.H.).
Russell V LuepkerDivision of Epidemiology and Community Health (K.L., B.S., R.V.L.), School of Public Health, University of Minnesota, Minneapolis.ORCID 0000-0003-1910-9543
John ConnettDivision of Biostatistics and Health Data Science (T.A.M., J.C.), School of Public Health, University of Minnesota, Minneapolis.
Sarah M WestbergDepartment of Pharmaceutical Care and Health Systems, College of Pharmacy, University of Minnesota, Minneapolis (S.M.W.).ORCID 0000-0002-3342-9554

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UM1TR004405 · NCATS · UNIVERSITY OF MINNESOTA · PI Bruce R Blazar, Damien A Fair · 2023 to 2026
$30.8M
mGlide RCT: A Clinical Glide Path to Close the Guideline-to-Practice Gap in HTN ManagementR01HL138332 · NHLBI · UNIVERSITY OF MINNESOTA · PI LAKSHMINARAYAN, KAMAKSHI · 2018 to 2022
$4.0M
mGlide-Care: A mHealth Partnership with Care Givers to Improve HTN Management in Patients with Cognitive ImpairmentK24AG078506 · NIA · UNIVERSITY OF MINNESOTA · PI KAMAKSHI LAKSHMINARAYAN · 2023 to 2026
$688k
NCATS NIH HHS UM1 TR004405NHLBI NIH HHS R01 HL138332NIA NIH HHS K24 AG078506
6 · The paper itself

Abstract

backgroundThe mGlide RCT (randomized controlled trial) evaluated whether a pharmacist-led, mobile health technology facilitated care model improves hypertension control in diverse populations.

methodsWe recruited adult English, Spanish, or Hmong-speaking patients with uncontrolled hypertension from a large health care system and smaller community clinics serving low-income patients. Participants were randomized 1:1 to mGlide or usual care. The 6-month intervention included daily blood pressure (BP) self-monitoring using a smartphone and wireless monitor, automated app-based data sharing, and responsive medication adjustment by a pharmacist-led provider-team. Comparison participants received a digital monitor. Outcomes included mean 6-month systolic BP (SBP), 12-month sustained BP control, 24-hour ambulatory BP and patient activation.

resultsA total of 395 participants (mean age, 66.9 years; 46.6% women; mean [SD] SBP, 143.4 [16.5] mm Hg) were randomized to mGlide (n=198) or usual care (n=197). Mean (SD) 6-month SBP (mm Hg) was lower in the mGlide arm (128.1 [13.9] versus 134.0 [16.0]). The adjusted mean difference between groups for the primary outcome of 6-month SBP favored mGlide: -5.8 mm Hg (95% CI, -8.6 to -3.0), sustained at 12 months (-5.7 mm Hg [-8.7 to -2.6]). The mGlide arm also had a 4.8 mm Hg (

conclusionsA mobile health-facilitated care model with pharmacist-led medication adjustment was effective in lowering BP in diverse populations. Patients with low activation benefited more from the intervention; activation levels may inform efficient intervention selection. REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT03612271.

Indexed as

Antihypertensive AgentsHypertensionTelemedicineAdherence InterventionsAgedBlood PressureBlood Pressure Monitoring, AmbulatoryDigital HealthFemaleHumansMaleMiddle AgedRemote Patient MonitoringAntihypertensive Agentsblood pressure monitoring, ambulatoryhypertensionpharmaciststelemedicine

Identifiers

PMID41717677
PMCPMC12927611

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.