Evidence map›Paper›PMID 41717630›Full record

ArticleCurrent research in food science2026

Decoding Tocopherol-Polyphenol interactions in oil-in-water emulsions through combined WIM-CAT and CV assays.

Camille Robichon, Erwann Durand, Jayaruwan G Gamaethiralalage, Philippe Bohuon, Bruno Baréa, Nathalie Barouh, Francis Courtois, Frédéric Fine, Louis C P M de Smet, Pierre Villeneuve

Abstract read
In one paragraph

Article in Current research in food science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Camille RobichonCIRAD, UMR QualiSud, Montpellier, F-34398, France.
Erwann DurandCIRAD, UMR QualiSud, Montpellier, F-34398, France.
Jayaruwan G GamaethiralalageWageningen University & Research, Laboratory of Organic Chemistry, 4 Stippeneng, Wageningen, 6708 WE, the Netherlands.
Philippe BohuonQUALISUD, Univ Montpellier, Avignon Université, CIRAD, Institut Agro, IRD, Université de La Réunion, Montpellier, France.
Bruno BaréaCIRAD, UMR QualiSud, Montpellier, F-34398, France.
Nathalie BarouhCIRAD, UMR QualiSud, Montpellier, F-34398, France.
Francis CourtoisQUALISUD, Univ Montpellier, Avignon Université, CIRAD, Institut Agro, IRD, Université de La Réunion, Montpellier, France.
Frédéric FineTERRES INOVIA, Parc Industriel - 11 Rue Monge, Pessac, 33600, France.
Louis C P M de SmetWageningen University & Research, Laboratory of Organic Chemistry, 4 Stippeneng, Wageningen, 6708 WE, the Netherlands.
Pierre VilleneuveCIRAD, UMR QualiSud, Montpellier, F-34398, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The antioxidant interactions of α- and γ-tocopherol with curcumin and quercetin were assessed in an oil-in-water emulsion using the WIM-CAT assay, a method integrating Weibull interaction modeling with the conjugated autoxidizable triene technique. Synergistic effects were strongest for γ-tocopherol with curcumin and for α-tocopherol with quercetin, particularly at low tocopherol concentrations (0.2 μM in emulsion, 380 ppm in oil) and high molar ratios (3:1). Increasing tocopherol concentration to 0.6 μM in emulsion (1140 ppm in oil) reduced synergy, likely reflecting pro-oxidant activity. The presence of ferrous ions accelerated oxidation but did not influence synergistic interactions, while acidic conditions reduced tocopherol pro-oxidation and modified the effects of curcumin and quercetin. Weibull modeling revealed isoform-dependent differences during the propagation phase of oxidation. Cyclic voltammetry further suggested that the synergy of α-tocopherol may involve antioxidant regeneration mechanisms, whereas γ-tocopherol appears to act through alternative redox processes. Together, kinetic and electrochemical analyses provide complementary insights into the conditions governing antioxidant interactions.

Indexed as

AntioxidantsCurcuminCyclic voltammetryModellingQuercetinSynergyTocopherols

Identifiers

PMID41717630
PMCPMC12914691

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.