ReviewFrontiers in cardiovascular medicine2026
Research progress on macrophage regulation of atherosclerosis.
Review in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiovascular diseases (CVDs) currently are responsible for high disability and mortality rates worldwide. Atherosclerosis is a major pathological process leading to CVDs, and macrophages are known to be important contributors to the initiation of atherosclerosis and promotion of plaque development, which eventually leads to plaque rupture. The role of these cells as a driver of plaque instability has received widespread attention, with continued research efforts devoted to unraveling the underlying mechanisms of macrophage involvement in atherosclerosis and identifying specific therapeutic strategies. In this review, we summarize the current evidence regarding the mechanisms by which macrophages regulate the progression of plaque development as well as recent therapeutic advances for the treatment and prevention of atherosclerosis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.