Evidence map›Paper›PMID 41717417›Full record

ReviewFrontiers in oncology2026

Cross-disciplinary communication between oral and gut microbiota in head and neck cancer.

Xinhua Lin, Hanbin Qin, Zhonglu Liu, Xin Zhao, Xuexia Liu, Hua Zhang

Erratum issuedAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Xinhua LinSchool of Clinical Medicine, Shandong Second Medical University, Weifang, China.
Hanbin QinSchool of Clinical Medicine, Shandong Second Medical University, Weifang, China.
Zhonglu Liu *Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China.
Xin ZhaoDepartment of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China.
Xuexia Liu *Shandong Stem Cell Engineering Technology Research Center, Central Laboratory, Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, China.
Hua Zhang *Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Head and neck cancer (HNC) is a prevalent malignancy with a rising global incidence. While traditional risk factors such as tobacco use and viral infections are well-established, the dysbiosis of oral and gut microbiota has recently emerged as a pivotal contributor to HNC pathogenesis. The oral-gut axis serves as a critical conduit for bidirectional microbial crosstalk, facilitated by bacterial translocation, metabolic exchange, and immune modulation, collectively fostering a pro-tumorigenic microenvironment. Key oral pathogens, including

Indexed as

gut microbiotaHNCoral-gut axisoral microbiotatumor

Identifiers

PMID41717417
PMCPMC12913109

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.