Evidence map›Paper›PMID 41717410›Full record

ReviewFrontiers in oncology2026

Stereotactic body radiation therapy for hepatocellular carcinoma: a comprehensive review.

Yupeng Di, Gang Ren, Yingjie Wang, Lingling Meng, Jing Li

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yupeng Di *Department of Radiation Protection Medicine, School of Preventive Medicine, Fourth Military Medical University, Xi'an, China.
Gang Ren *Department of Radiotherapy, Peking University Shougang Hospital, Beijing, China.
Yingjie WangDepartment of Radiation Oncology, Air Force Medical Center, People's Liberation Army (PLA), Beijing, China.
Lingling MengDepartment of Radiation Oncology, Senior Department of Oncology, The First Medical Center of People's Liberation Army (PLA) General Hospital, Beijing, China.
Jing LiDepartment of Radiation Protection Medicine, School of Preventive Medicine, Fourth Military Medical University, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) presents significant challenges in modern surgical and radiation oncology, primarily due to biological heterogeneity and the complexities of underlying liver cirrhosis. This review evaluates stereotactic body radiation therapy (SBRT) as a mature, curative-intent modality within the multidisciplinary management of primary hepatic malignancies. Drawing parallels with high-dose-per-fraction successes in early-stage non-small cell lung cancer, pancreatic adenocarcinoma, and spinal metastases, we analyze the physical evolution, radiobiological principles, and functional dosimetric constraints specific to the hepatic microenvironment. Specifically, we examine advanced motion management, distinguishing pre-treatment setup from real-time intrafractional monitoring via kilovoltage projection streaming images (kV-PSI) and MR-guidance. We evaluate the prognostic value of metabolic imaging parameters, specifically

Indexed as

efficacyhepatocellular carcinomaimmunotherapystereotactic body radiation therapytreatment outcomes

Identifiers

PMID41717410
PMCPMC12914947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.