Evidence map›Paper›PMID 41717272›Full record

ArticleParasite epidemiology and control2026

A 10-year registry-based retrospective study of cutaneous Leishmaniasis in Mashhad, northeastern Iran: Demographic, clinical, and therapeutic profiles of 1537 cases.

Vahid Mashayekhi-Goyonlo, Pouran Layegh, Zahra Ghasemi, Masomeh Hosseini-Nezhad, Ali Tajik

Abstract read
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Article in Parasite epidemiology and control, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Vahid Mashayekhi-GoyonloCutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Pouran LayeghCutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Zahra GhasemiCutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Masomeh Hosseini-NezhadCutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Ali TajikCutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cutaneous leishmaniasis (CL) remains one of the most prevalent neglected tropical diseases, imposing a substantial health burden in many developing countries. Given the importance of epidemiological data in guiding public health responses, this retrospective registry-based study aimed to describe and compare the epidemiological, demographic, clinical, and therapeutic characteristics of CL among patients referred to the Cutaneous Leishmaniasis Research Centers in Mashhad, Northeastern Iran, between 2015 and 2024. Methods: This retrospective case-series included all patients ( Results: Among 1537 confirmed CL cases, children under 10 years accounted for the largest proportion (34.9%). Male patients were slightly more frequent than females (52.3%). The majority had low educational levels (71.6%) and resided in peri-urban areas (59.4%). Almost all cases were localized (99.4%), with lesions predominantly on exposed areas such as the head and neck (47.0%) and upper extremities (38.6%). The most common clinical forms were papulonodular (50.4%), ulcerative (31.0%), and plaque-type lesion (13.7%). Intralesional antimony was the most frequent treatment (59.3%), and approximately 63% of treated patients achieved complete cure. Seasonally, case numbers peaked in autumn, declined in winter, and rose again in spring. Conclusion: CL remains a major public health concern in Mashhad, Iran. Despite encouraging cure rates, the true disease burden is likely underestimated. Demographic and climatic factors influence its distribution. Longitudinal and clinical studies are warranted to better understand treatment outcomes. Strengthened surveillance, public awareness, and coordinated control programs are crucial for sustainable disease management.

Indexed as

Cutaneous leishmaniasisEpidemiologyIranRetrospective studyTreatment outcomes

Identifiers

PMID41717272
PMCPMC12914280

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