Evidence map›Paper›PMID 41717221›Full record

SynthesisFrontiers in aging neuroscience2026

Research trends on neuroinflammation in Parkinson's disease: an exploratory analysis.

Yan-Jun Chen, Ming-Rong Xie, Fang Liu, Sheng-Qiang Zhou, Bo Li

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in aging neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yan-Jun Chen *The First Hospital of Hunan University of Chinese Medicine, Changsha, China.
Ming-Rong Xie *The First Clinical College of Nanjing University of Chinese Medicine, Nanjing, China.
Fang LiuNational TCM Master Liu Zuyi Inheritance Studio, Hunan Provincial Hospital of Integrated Traditional Chinese and Western Medicine (The Affiliated Hospital of Hunan Academy of Traditional Chinese Medicine), Changsha, China.
Sheng-Qiang ZhouNational TCM Master Liu Zuyi Inheritance Studio, Hunan Provincial Hospital of Integrated Traditional Chinese and Western Medicine (The Affiliated Hospital of Hunan Academy of Traditional Chinese Medicine), Changsha, China.
Bo LiThe First Hospital of Hunan University of Chinese Medicine, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Neuroinflammation is a core mechanism in the pathogenesis of Parkinson's disease (PD). Research on PD and neuroinflammation has been steadily increasing. This study aims to explore and analyze the current status, hotspots, and future directions of neuroinflammation-associated research in PD. Method: Data were retrieved from the Web of Science and PubMed databases. CiteSpace, VOSviewer, and the R package bibliometrix were used for data analysis and visualization. Results: Publications on neuroinflammation in PD showed an upward trend. China had the most publications, while Norway exhibited the greatest influence. Shanghai Jiao Tong University was the most prolific institution, whereas Arizona State University demonstrated the strongest influence. The International Conclusion: Over the past two decades, research on neuroinflammation in PD has been continuously increasing. The research hotspots included microglia, oxidative stress,

Indexed as

alpha-synucleingut microbiotamicroglianeuroinflammationoxidative stressParkinson’s disease

Identifiers

PMID41717221
PMCPMC12913463

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.