Evidence map›Paper›PMID 41717190›Full record

ArticleCureus2026

Retrograde Type A Aortic Dissection With a Double Aortic Valve Sign Presenting As Acute Coronary Syndrome: A Case Report and Literature Review.

Karim M Elzoghby, Raffi Almutawa, Rania S Ahmed, Salah N El-Tallawy, Joseph V Pergolizzi, Abdullah T Alsubaie, Giustino Varrassi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Karim M ElzoghbyCardiology, Saudi German Hospital Riyadh, Riyadh, SAU.
Raffi AlmutawaCardiology, Alfaisal University, Riyadh, SAU.
Rania S AhmedCollege of Medicine, Alfaisal University, Riyadh, SAU.
Salah N El-TallawyAnesthesia and Pain Management, Faculty of Medicine, National Cancer Institute (NCI) Cairo University, Cairo, EGY.
Joseph V PergolizziPain Management, NEMA Research Inc., Naples, USA.
Abdullah T AlsubaieAnesthesia, King Abdulaziz University Hospital, Jeddah, SAU.
Giustino VarrassiPain Medicine, Paolo Procacci Foundation, Rome, ITA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute type A aortic dissection (ATAAD) is a time-sensitive and life-threatening emergency that usually presents as sudden, severe pain radiating to the back. Atypical presentations such as acute coronary syndromes make it challenging to diagnose, hence delaying the management. We report a case of a 57-year-old male with a history of hypertension, diabetes, dyslipidemia, and chronic smoking who presented to the emergency department with central chest heaviness that radiated to the left hand associated with diaphoresis. Normal cardiac enzymes and an electrocardiogram (ECG) led to the initial diagnosis of unstable angina. As a result, he was given dual antiplatelets, which provided temporary relief of his symptoms. However, before discharge, a bedside transthoracic echocardiography found a retrograde ATAAD with the double aortic valve sign, a rare echocardiographic finding, along with severe aortic regurgitation. Further imaging with CT angiography confirmed the diagnosis despite the patient not complaining of any pain. Due to the involvement of the aortic root, valve, and right coronary artery, he underwent the Bentall procedure. Postoperative management emphasized initiation of anticoagulation, controlling the blood pressure, and management of cardiovascular risk factors to prevent aortic dissection and aneurysm. The patient recovered from the postoperative course without complications and remained stable upon follow-up. ATAAD should remain in the differential diagnosis for acute chest pain even in the absence of a typical presentation. Bedside echocardiography is a useful initial diagnostic tool, and early multidisciplinary management supports successful patient outcomes.

Indexed as

acute aortic dissectionacute chest painatypical presentation of aortic dissectiondouble aortic valve signmisdiagnosed acute coronary syndromemisdiagnosed aortic dissectionretrograde type a acute aortic dissectionretrograde type a dissection

Identifiers

PMID41717190
PMCPMC12916025

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.