Evidence map›Paper›PMID 41717091›Full record

ArticleFrontiers in microbiology2025

Panton-Valentine Leukocidin and concurrent respiratory viral infection as risk factors for fatal

Liting Zhou, Shiqi Guo, Ting Zhang, Ruru Bi, Qingzhen Han, Qiang Guo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liting Zhou *Center of Clinical Laboratory, The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital), Suzhou, China.
Shiqi Guo *Department of Emergency, The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital), Suzhou, China.
Ting ZhangCenter of Clinical Laboratory, The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital), Suzhou, China.
Ruru BiCenter of Clinical Laboratory, The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital), Suzhou, China.
Qingzhen HanCenter of Clinical Laboratory, The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital), Suzhou, China.
Qiang GuoDepartment of Emergency, The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital), Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: We conducted a retrospective cohort study of all SAB cases at our institution (Jan 2021-Mar 2025), expanding from an initial analysis of four fatal cases. Patient profiles, clinical characteristics and microbiological features were analyzed. Independent risk factors for mortality were determined through multivariate logistic regression. Results: Among 40 patients, mortality was higher in the community-associated Conclusion: PVL-producing strains, especially ST22, are key mortality drivers in SAB, with effects amplified by respiratory viral co-infection. Early recognition of PVL/viral co-infection and comorbidity management are critical for improving outcomes.

Indexed as

bacteremiahyper-virulent ST22Panton-Valentine Leukocidinrespiratory viral infectionStaphylococcus aureus

Identifiers

PMID41717091
PMCPMC12913544

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.