Evidence map›Paper›PMID 41717049›Full record

ArticleJTO clinical and research reports2026

ALK Inhibitor Response in Novel

Charles Hsu, Mohamed Yakoub, Michael Offin, Juliana Eng, Alexander Drilon, Soo-Ryum Yang

Abstract readCase Reports
In one paragraph

Article in JTO clinical and research reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. RareJTO clinical and research reports · 2026
    Article
  2. Article
4 · The record

Corrections and comments

  • Commented on by
    Rare2026
5 · Who and what money

Authors and funding

6 authors.

Charles HsuMemorial Sloan Kettering Cancer Center, New York, New York.
Mohamed YakoubMemorial Sloan Kettering Cancer Center, New York, New York.
Michael OffinMemorial Sloan Kettering Cancer Center, New York, New York.
Juliana EngMemorial Sloan Kettering Cancer Center, New York, New York.
Alexander DrilonMemorial Sloan Kettering Cancer Center, New York, New York.
Soo-Ryum YangMemorial Sloan Kettering Cancer Center, New York, New York.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
The Role of Focal Oncogene Amplifications in Lung CancerP01CA129243 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Andrea Ventura · 2007 to 2026
$31.2M
NCI NIH HHS P01 CA129243NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Background: Case Presentation: We report two patients with metastatic NSCLC harboring novel Conclusions: These cases expand the landscape of noncanonical

Indexed as

ALK fusionanaplastic lymphoma kinasenext-generation sequencingnovel fusion partnersNSCLC

Identifiers

PMID41717049
PMCPMC12914274

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.