ArticleSmall science2026
Lewis Acid-Triggered Spatiotemporally Controllable Ring Opening in a Classic Rhodamine Featuring Φ = 95% Emission.
Article in Small science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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5 authors.
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Abstract
Rhodamine derivatives, as a prominent class of fluorophores, have become indispensable in advanced material engineering and biomedical research due to their exceptional photostability and tunable optical characteristics. However, their practical implementation faces fundamental challenges: conventional proton-mediated spirolactone ring opening mechanisms severely compromise fluorescence performance, while conventional structural optimization approaches remain synthetically demanding with limited efficacy. We hereby present a novel Lewis acid-assisted activation strategy that enables reversible spirolactone ring opening in classical rhodamine systems. This innovative approach achieves remarkable fluorescence enhancement characterized by superior quantum yields (up to 95%) and prolonged excited state lifetimes. Notably, the Lewis acid coordination establishes precise photocontrol over the ring opening process. This breakthrough represents the first demonstration of a nondestructive activation pathway for rhodamine fluorophores, effectively converting the nonemissive spirolactone form into highly luminescent Lewis acid complexes while maintaining molecular integrity.
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