ArticleAdvances in radiation oncology2026
Real-World Data on Barrigel and SpaceOAR Rectal Spacers in Prostate Cancer Radiation Therapy: A Comparative Analysis.
Article in Advances in radiation oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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9 authors.
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Abstract
Purpose: Methods and Materials: A multicenter retrospective analysis was performed on all men with prostate cancer undergoing radiation therapy from 2017 to 2023. Demographic, radiation therapy, and magnetic resonance imaging details were imported for analysis. Each multiparametric magnetic resonance imaging was scored on rectal spacing placement by 2 independent observers. Results: Eight hundred twenty-two patients were included for dosimetric and 605 for quality of insertion analysis. The median SpaceOAR volume (13.80 cc) was larger than the median Barrigel volume (5.10 cc) ( Conclusions: Real-world data show that SpaceOAR achieves better dosimetry than Barrigel likely due to larger insertion volumes. At similar insertion volumes, Barrigel achieves lower irradiated rectal volumes compared to SpaceOAR. Dosimetric outcomes are more likely impacted by volume rather than symmetry of insertion. The SQS scoring method may have better utility than the FV scoring method for assessing dosimetric outcomes. Our data also indicate that Barrigel has a lower incidence of rectal wall infiltration compared with SpaceOAR.
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