ArticleOxford medical case reports2026
From vision to vital signs: uncovering severe Anemia through retinal clues!
Article in Oxford medical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
A 28-year-old woman presented in the emergency with sudden, painless bilateral loss of vision over one week. Fundus examination revealed multiple white-centered retinal hemorrhages (Roth spots), cotton wool spots, and multiple retinal hemorrhages in both eyes, indicative of anemic retinopathy. Laboratory evaluation showed profound pancytopenia: hemoglobin 2.3 g/dl, leukocyte count 3.0 × 10^9/l, platelet count 92 × 10^9/l, with elevated mean corpuscular volume (107 fl). Serum cobalamin (vitamin B12) was 57 pg/ml and folate 3.5 ng/ml, consistent with megaloblastic anemia due to vitamin B12 deficiency. Peripheral blood smear confirmed macro-ovalocytes and hypersegmented neutrophils. The patient was managed emergently with packed red blood cell transfusions and parenteral vitamin B 12 and folate supplementation. Two weeks later, her hemoglobin had improved to 10.1 g/dl, and follow-up fundus examination showed marked resolution of retinal hemorrhages and Roth spots with partial visual recovery. This case highlights that severe megaloblastic anemia can present as an acute ophthalmic emergency.
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