Evidence map›Paper›PMID 41716903›Full record

ArticleEuropean heart journal open2026

Left ventricular diastolic volume on cardiac magnetic resonance and risk of incident heart failure.

Julio Núñez, Gema Miñana, Miguel Lorenzo, Rafael de la Espriella, Agustín Fernández-Cisnal, Nerea Perez, Elena De Dios, Jose Gavara, Cesar Rios-Navarro, Victor Marcos-Garces and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European heart journal open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Julio NúñezCardiology Department, Hospital Clínico Universitario de Valencia, Avenida Blasco Ibáñez 17, Valencia CP 46010, Spain.ORCID https://orcid.org/0000-0003-1672-7119
Gema MiñanaCardiology Department, Hospital Clínico Universitario de Valencia, Avenida Blasco Ibáñez 17, Valencia CP 46010, Spain.ORCID https://orcid.org/0000-0001-8777-2588
Miguel LorenzoCardiology Department, Hospital Clínico Universitario de Valencia, Avenida Blasco Ibáñez 17, Valencia CP 46010, Spain.ORCID https://orcid.org/0000-0002-2131-8443
Rafael de la EspriellaCardiology Department, Hospital Clínico Universitario de Valencia, Avenida Blasco Ibáñez 17, Valencia CP 46010, Spain.ORCID https://orcid.org/0000-0002-8720-3999
Agustín Fernández-CisnalCardiology Department, Hospital Clínico Universitario de Valencia, Avenida Blasco Ibáñez 17, Valencia CP 46010, Spain.ORCID https://orcid.org/0000-0002-0672-0696
Nerea PerezInstituto de Investigación Sanitaria INCLIVA, Calle Menéndez y Pelayo, 4, Valencia 46010, Spain.ORCID https://orcid.org/0000-0003-3527-0337
Elena De DiosCentro de Investigación Biomédica en Red - Cardiovascular (CIBER-CV), Calle Monforte de Lemos, 3-5, Pabellón 11, Madrid 28029, Spain.ORCID https://orcid.org/0000-0002-9620-8839
Jose GavaraInstituto de Investigación Sanitaria INCLIVA, Calle Menéndez y Pelayo, 4, Valencia 46010, Spain.ORCID https://orcid.org/0000-0002-3483-7066
Cesar Rios-NavarroInstituto de Investigación Sanitaria INCLIVA, Calle Menéndez y Pelayo, 4, Valencia 46010, Spain.ORCID https://orcid.org/0000-0002-6405-6279
Victor Marcos-GarcesCardiology Department, Hospital Clínico Universitario de Valencia, Avenida Blasco Ibáñez 17, Valencia CP 46010, Spain.
Hector MerencianoCardiology Department, Hospital Clínico Universitario de Valencia, Avenida Blasco Ibáñez 17, Valencia CP 46010, Spain.ORCID https://orcid.org/0000-0002-1734-0381
Juan SanchisCardiology Department, Hospital Clínico Universitario de Valencia, Avenida Blasco Ibáñez 17, Valencia CP 46010, Spain.ORCID https://orcid.org/0000-0002-6831-7296
Antoni Bayés-GenísCardiology Department, Hospital Universitari Germans Trias I Pujol, Carretera de Canyet, s/n, 08916 Badalona, Barcelona, Spain.
Markus MeyerDepartment of Medicine, Lillehei Heart Institute, University of Minnesota College of Medicine, 2231 6th Street SE, Suite 4-156 Minneapolis, MN 55455, USA.ORCID https://orcid.org/0000-0001-9361-5458
Vicent BodíCardiology Department, Hospital Clínico Universitario de Valencia, Avenida Blasco Ibáñez 17, Valencia CP 46010, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: We explored the association between indexed left ventricular end-diastolic volume (iLVEDV) on cardiac magnetic resonance (CMR) and the risk of incident heart failure (HF) (stage C) in patients with suspected coronary heart disease without overt HF (stages A and B). We also examined the risk-modifying effect of left ventricular ejection fraction (LVEF) and sex. Methods and results: We retrospectively included 5471 patients who underwent vasodilator stress CMR for suspected coronary artery disease and without a history of HF. Multivariate Cox proportional hazards regression adapted for competing events models assessed the relationship between iLVEDV and new-onset HF (stage C), considering LVEF status as a potential modifier. The mean age was 651 ± 11.6 years, and 2123 (38.8%) were women. The medians of CMR-iLVEDV and CMR-LVEF were 67 mL/m Conclusion: In subjects with higher LVEF, smaller left ventricle volumes identified a subset of patients with an increased risk of incident HF. These findings reveal a need for a better understanding of the pathophysiological mechanisms of HF with supranormal ejection fraction.

Indexed as

Cardiac magnetic resonanceHeart failureLeft ventricle ejection fractionLeft ventricle volumesSex

Identifiers

PMID41716903
PMCPMC12915573

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.