Evidence map›Paper›PMID 41716885›Full record

ReviewPulmonary circulation2026

Right Ventricular Pressure-Volume Loop Analysis in Large Animal Research: A Scoping Review of Current Practices Using Conductance and Admittance Catheters.

Michaela Orlitová, Joachim Hellinck, Mads Dam Lyhne, Asger Granfeldt, Arne P Neyrinck, Tom Verbelen, Piet Claus

Abstract readReview
In one paragraph

Review in Pulmonary circulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michaela OrlitováDepartment of Cardiovascular Sciences KU Leuven Leuven Belgium.ORCID https://orcid.org/0000-0002-5295-9315
Joachim HellinckDepartment of Cardiovascular Sciences KU Leuven Leuven Belgium.ORCID https://orcid.org/0009-0005-6374-6373
Mads Dam LyhneDepartment of Clinical Medicine Aarhus University Aarhus Denmark.ORCID https://orcid.org/0000-0001-5279-260X
Asger GranfeldtDepartment of Clinical Medicine Aarhus University Aarhus Denmark.ORCID https://orcid.org/0000-0002-7241-6131
Arne P NeyrinckDepartment of Cardiovascular Sciences KU Leuven Leuven Belgium.ORCID https://orcid.org/0000-0001-9930-8045
Tom VerbelenDepartment of Cardiovascular Sciences KU Leuven Leuven Belgium.ORCID https://orcid.org/0000-0003-1461-3986
Piet ClausDepartment of Cardiovascular Sciences KU Leuven Leuven Belgium.ORCID https://orcid.org/0000-0002-2013-639X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Right ventricular (RV) function assessment using catheter-derived pressure-volume (PV) loops is used in translational research, providing detailed insights into cardiac mechanics. Its practical implementation requires methodological accuracy to ensure rigor, reproducibility and transparency. However, current practices for PV loop acquisition are set at individual laboratories, resulting in overall practice remaining largely unknown. This study aimed to explore current practices in RV PV loop acquisition in large animal research. We therefore conducted a scoping review registered on the Open Science Framework and guided by PRISMA Extension for Scoping Reviews, with comprehensive searches in PubMed, Embase, Scopus, and Web of Science (December 2024). Eligible studies included large animal models published after 2014 using conductance or admittance catheters. Out of 5133 identified records, 62 met inclusion criteria. The review revealed underreporting and substantial variability in methodology, particularly in catheter placement, calibration, and ventilatory mode during PV loop recording. Catheter insertion sites included RV inflow (42%) and outflow tracts (19.4%); fluoroscopy was used in 51.6%. Calibration was not reported in one-third of studies. Loop recording during apnea were reported in 23%, mechanical ventilation in 26%, and was not specified in 51%. Overall, RV PV loop protocols show substantial heterogeneity, highlighting the need for standardized methodological reporting, to improve transparency, research reproducibility and translational significance. Expert consensus is warranted to establish methodological guidelines.

Indexed as

calibrationmethodologyRV hemodynamic monitoring

Identifiers

PMID41716885
PMCPMC12914149

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.