Evidence map›Paper›PMID 41716866›Full record

ArticleInternational journal of endocrinology and metabolism2025

The Impact of the COVID-19 Pandemic on Osteoporosis Diagnosis and Treatment in Iran: A National Study.

Sepideh Hajivalizadeh, Mahnaz Sanjari, Kazem Khalagi, Mohammad Javad Mansourzadeh, Saeed Shahsavari, Amirhossein Aghakhani, Mohammad Effatpanah, Zahra Shahali, Fatemeh Hajivalizadeh, Pardis Zarepour and 4 more

Abstract read
In one paragraph

Article in International journal of endocrinology and metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sepideh HajivalizadehOsteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-0393-1196
Mahnaz SanjariOsteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-2992-6184
Kazem KhalagiOsteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-0890-6232
Mohammad Javad MansourzadehPrevention of Metabolic Disorders Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Saeed ShahsavariDepartment of Biostatistics and Epidemiology, School of Health, Alborz University of Medical Sciences, Karaj, Iran.
Amirhossein AghakhaniOsteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-1804-6034
Mohammad EffatpanahDepartment of Pediatric, Imam Khomeini Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-6855-4945
Zahra ShahaliNational Center for Health Insurance Research, Tehran, Iran.ORCID https://orcid.org/0000-0002-5457-5999
Fatemeh HajivalizadehDepartment of Public Health, Center for Non-communicable Disease Control and Prevention, Ministry of Health and Medical Education, Tehran, Iran.
Pardis ZarepourDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Parastoo MontazerlotfEpidemiology and Biostatistics Unit, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Elahe HesariOsteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Noushin FahimfarOsteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Afshin OstovarEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The emergence of the COVID-19 pandemic disrupted the management of non-communicable diseases, including osteoporosis. Objectives: This study aims to investigate the impact of the COVID-19 pandemic on osteoporosis diagnosis and treatment in Iran. Methods: This cross-sectional study evaluated changes in the number of prescriptions for osteoporosis diagnosis and treatment before and during the COVID-19 pandemic from all available and complete data. Data on the number of prescriptions for bone mineral density (BMD) tests, osteoporosis-related lab tests (serum vitamin D level and serum calcium level), and medications (alendronate and calcitonin) were obtained from the Iran Health Insurance Organization (IHIO) dataset from March 2019 to March 2022. Additionally, the University of Sheffield provided the number of fracture risk assessment tool (FRAX Results: A total number of 4,901,027 prescriptions composed of 62,718 prescriptions for BMD tests, 2,862,871 prescriptions for serum vitamin D level tests, and 1,952,600 prescriptions for serum calcium level tests regarding diagnosis, and a total number of 446,791 prescriptions, including 388,519 alendronate and 58,272 calcitonin prescriptions regarding treatment, were evaluated. A statistically significant decrease in the number of prescriptions for BMD test and FRAX Conclusions: The present study demonstrated that the COVID-19 pandemic negatively affected the diagnosis and treatment of osteoporosis. However, it was limited by the lack of data on prescriptions for other osteoporosis medications and diagnostic tests, the lack of access to the data on prescriptions for people whose costs are not covered by the IHIO, and the restricted data access regarding the presented data. The findings are based on prescription-level data in Iran and primarily reflect practice within this healthcare context; therefore, caution is required when generalizing to settings with different healthcare systems or population structures. Further studies are needed to assess this impact and to help prevent management disruption in future health crises.

Indexed as

AlendronateBone Mineral Density (BMD)CalcitoninDiagnosisDisease ManagementMedicationOsteoporosisSARS-CoV-2Treatment

Identifiers

PMID41716866
PMCPMC12915347

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.