ArticleGastro hep advances2026
ScRNA-seq Identifies High CXCL8 Linked to Liver Fibrosis in HBeAg-negative Chronic Hepatitis B Patients With Low HBsAg.
Article in Gastro hep advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Chemokine ligand 8 (CXCL8) is suggested as a potential biomarker in assessing the progression and severity of hepatitis B e antigen-negative treatment-naive patients with "chronic hepatitis". Analysis of CXCL8 expression in the liver and blood of such patients with low and high hepatitis B surface antigen (HBsAg) levels could provide insights into the immunopathogenesis of hepatitis B virus-related liver disease. Methods: Thirty-five hepatitis B e antigen-negative treatment-naive patients with "chronic hepatitis" patients were classified into Group I with HBsAg levels below 2000 IU/mL (HBsAg Results: HBsAg Conclusion: Elevated CXCL8 expression in plasma, peripheral, and intrahepatic mono-mac populations, along with distinct CD8 T-cell clusters, is associated with greater fibrosis in patients with low HBsAg levels.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.