Comparison of pre-weaning bovine respiratory disease treatment rates between non-vaccinated control and variably primed and boosted beef calves receiving commercially available bovine coronavirus vaccines.

Nathan E N Erickson, Tommy Ware, John Campbell, Kathy Larson, John A Ellis, Cheryl L Waldner

Abstract read

In one paragraph

Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nathan E N EricksonDepartment of Large Animal Clinical Sciences (Erickson, Campbell, Waldner) and Department of Microbiology (Ellis), Western College of Veterinary Medicine, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Veterinary Agri-Health Services, 281121 Dickson Stevenson Trail, Rocky View County, Alberta T4B 4L5 (Ware); Department of Animal Science, University of Saskatchewan, 54 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Larson).

Tommy WareDepartment of Large Animal Clinical Sciences (Erickson, Campbell, Waldner) and Department of Microbiology (Ellis), Western College of Veterinary Medicine, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Veterinary Agri-Health Services, 281121 Dickson Stevenson Trail, Rocky View County, Alberta T4B 4L5 (Ware); Department of Animal Science, University of Saskatchewan, 54 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Larson).

John CampbellDepartment of Large Animal Clinical Sciences (Erickson, Campbell, Waldner) and Department of Microbiology (Ellis), Western College of Veterinary Medicine, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Veterinary Agri-Health Services, 281121 Dickson Stevenson Trail, Rocky View County, Alberta T4B 4L5 (Ware); Department of Animal Science, University of Saskatchewan, 54 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Larson).

Kathy LarsonDepartment of Large Animal Clinical Sciences (Erickson, Campbell, Waldner) and Department of Microbiology (Ellis), Western College of Veterinary Medicine, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Veterinary Agri-Health Services, 281121 Dickson Stevenson Trail, Rocky View County, Alberta T4B 4L5 (Ware); Department of Animal Science, University of Saskatchewan, 54 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Larson).

John A EllisDepartment of Large Animal Clinical Sciences (Erickson, Campbell, Waldner) and Department of Microbiology (Ellis), Western College of Veterinary Medicine, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Veterinary Agri-Health Services, 281121 Dickson Stevenson Trail, Rocky View County, Alberta T4B 4L5 (Ware); Department of Animal Science, University of Saskatchewan, 54 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Larson).

Cheryl L WaldnerDepartment of Large Animal Clinical Sciences (Erickson, Campbell, Waldner) and Department of Microbiology (Ellis), Western College of Veterinary Medicine, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Veterinary Agri-Health Services, 281121 Dickson Stevenson Trail, Rocky View County, Alberta T4B 4L5 (Ware); Department of Animal Science, University of Saskatchewan, 54 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Larson).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The primary objective was to determine effectiveness of bovine coronavirus (BCoV) vaccination of neonatal calves in the face of natural respiratory infection in a commercial herd. Animals: At a privately owned ranch in north-central Alberta with a history of bovine respiratory disease (BRD), beef calves of mixed sex and breed were randomized into a clinical vaccine trial. Procedure: At birth, 447 calves were enrolled into the vaccine (VAC) group and administered an intranasal dose of BCoV vaccine, and 439 calves were enrolled as controls (CON). Most VAC calves ( Results: Calves in the CON group were more likely than VAC calves to be treated before turnout vaccination (OR: 1.50; Conclusion: Vaccination of neonatal calves with BCoV vaccine reduced the frequency of BRD treatment and total mortality and improved weaning weights and revenue potential in this herd. Clinical relevance: Vaccination with commercial BCoV vaccines could be an important tool to control neonatal BRD, particularly in herds with a history of disease not responsive to other BRD vaccines.

Indexed as

Bovine Respiratory Disease ComplexCattle DiseasesCoronavirus, BovineCoronavirus InfectionsVaccinationViral VaccinesAlbertaAnimalsAnimals, NewbornCattleFemaleMaleWeaningViral Vaccines

Identifiers

PMID41716505

PMCPMC12915464

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.