ArticleNature reviews bioengineering2023
Synthetic living materials in cancer biology.
Article in Nature reviews bioengineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Photo-excited extracellular electron transfer of electroactive microorganism triggers RAFT polymerization.Nature communications · 2025Article
- Matrix Stiffness and Biochemistry Govern Colorectal Cancer Cell Growth and Signaling in User-Programmable Synthetic Hydrogels.ACS biomaterials science & engineering · 2025Article
- Pancreatic cancer extracellular vesicles stimulate Schwann cell activation and perineural invasion in vitro via IL-8/CCL2.In vitro models · 2025Article
- Outlook and opportunities for engineered environments of breast cancer dormancy.Science advances · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Living materials, which are either made of and by living cells or synthetic with programmable elements catered to cells within, are environmentally responsive and can self-repair, allowing for controlled and predictable interactions with biological systems. Such features can also be achieved in purely synthetic materials by using chemical approaches to create dynamic and responsive materials that can undergo programmed changes, that can be remodelled by cells in a predictive way, sense their microenvironment and report back, or respond to remote triggers to rearrange in physical or chemical ways. In this Review, we discuss synthetic approaches to design such cell- and environment-responsive living materials, with a particular focus on their application in cancer. We highlight how synthetic and systems biology approaches can be implemented in the design of synthetic living materials and outline key cancer-related applications, including modelling of tumour heterogeneity, the tumour microenvironment and tumour evolution in response to therapy. Finally, we emphasize the importance of inclusive designs that should be based on an understanding of how health and disease manifest and impact humans from all racial and ethnic backgrounds, skin colors, sex, and genders.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.