ArticleHealth science reports2026
Predictive Value of White Blood Cell Counts for Infection in Patients With Diabetic Ketoacidosis and Rational Use of Antibiotics: A Cross-Sectional Study.
Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Nonspecific clinical presentations, absence of timely available paraclinical indicators of infection, and increasing concerns for antimicrobial resistance complicate decision-making in initiation of antibiotic therapy in patients with diabetic ketoacidosis (DKA). The authors have aimed to explore the role of white blood cell (WBC) counts as an indicator of infectious disease in patients with DKA. Methods: A retrospective observational study was conducted using data from patients hospitalized with DKA in a tertiary care center in Iran. Patient data was retrieved from the hospital information system (HIS). Associations between leukocytosis and leukopenia along with several paraclinical tests (including ESR and CRP levels) and a final diagnosis of infectious disease were examined. Results: Data from 129 patients were analyzed. Patients diagnosed with infection were significantly older ( Conclusions: We discourage the use of leukocytosis, per se, as a marker of infection in the setting of DKA. We found the absence of leukocytosis or leukopenia of high predictive value in exclusion of the possibility of infectious disease in DKA cases.
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