Evidence map›Paper›PMID 41716411›Full record

ArticleFrontiers in immunology2026

NMN protects cisplatin-associated AKI via NAD

Zhaozhi Wen, Jiazeng Wang, Yihang Yang, Longlong Chen, Xiangge Ji, Dong Liu, Chongxu Shi

Abstract read
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhaozhi Wen *School of Life Sciences, Nantong Laboratory of Development and Diseases, Nantong University, Nantong, Jiangsu, China.
Jiazeng Wang *School of Life Sciences, Nantong Laboratory of Development and Diseases, Nantong University, Nantong, Jiangsu, China.
Yihang Yang *School of Life Sciences, Nantong Laboratory of Development and Diseases, Nantong University, Nantong, Jiangsu, China.
Longlong ChenSchool of Life Sciences, Nantong Laboratory of Development and Diseases, Nantong University, Nantong, Jiangsu, China.
Xiangge JiSchool of Life Sciences, Nantong Laboratory of Development and Diseases, Nantong University, Nantong, Jiangsu, China.
Dong LiuSchool of Life Sciences, Nantong Laboratory of Development and Diseases, Nantong University, Nantong, Jiangsu, China.
Chongxu ShiSchool of Life Sciences, Nantong Laboratory of Development and Diseases, Nantong University, Nantong, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute kidney injury (AKI) is a critical public health concern with high morbidity and mortality. The chemotherapy agent cisplatin is widely used for various solid tumors; however, cisplatin-associated AKI (CIS-AKI) is a frequent complication in the clinic. Nicotinamide adenine dinucleotide (NAD

Indexed as

Acute Kidney InjuryCisplatinNADNicotinamide MononucleotideSirtuin 1AnimalsAntineoplastic AgentsCell LineDisease Models, AnimalHumansKidneyMaleMiceMice, Inbred C57BLSignal TransductionAntineoplastic AgentsCisplatinNADNicotinamide MononucleotideSirt1 protein, mouseSirtuin 1acute kidney injurycisplatininflammationnicotinamide adenine dinucleotideSIRT1

Identifiers

PMID41716411
PMCPMC12913174

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.