ReviewChemical science2026
Control over stereogenic centres beyond tetracoordination.
Review in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In contrast to conventional tetracoordinate stereogenic centres exhibiting twofold stereogenicity, penta- and hexacoordinate stereogenic centres may encode more than two stereoisomers, expanding the stereochemical space accessible to these species. This more complex stereoisomerism is characteristic to compounds of a variety of main-group elements and transition metals having a suitable set of ligands. Despite these unique hallmarks and the prospective applications in medicinal chemistry, catalysis, and information science, this area of stereoselective synthesis awaits widespread exploration. In this review, the fundamentals of the higher-order stereogenicity of penta- and hexacoordinate stereogenic centres will thus be summarized and an overview of emerging applications and their stereoselective synthesis will be provided.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.