ArticleNeurophotonics2026
Decreased brain activity within the dorsolateral prefrontal cortex in adolescents during cognitive control tasks: a functional near-infrared spectroscopy study.
Article in Neurophotonics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Significance: Adolescents with attention-deficit/hyperactivity disorder (ADHD) have reduced dorsolateral prefrontal cortex (DLPFC) activation during cognitive control tasks and weaker attention performance, with higher DLPFC activity linked to better complex attention, showing a connection between neural function and behavior. These findings support prefrontal dysfunction and hemispheric asymmetry in ADHD adolescents. Aim: We aimed to compare brain activation during cognitive control tasks between adolescents with ADHD and typically developing (TD) individuals using functional near-infrared spectroscopy (fNIRS). Results: The ADHD group recorded decreased scores for congruence and incongruence of ST compared with the TD group. TD adolescents showed significantly greater increases in oxygenated hemoglobin concentration ( Conclusions: We found distinct brain activation patterns in the DLPFC for ADHD adolescents during cognitive control tasks. fNIRS measured these differences, helping to understand the developmental trajectory of ADHD in adolescents and providing evidence of functional impairment in complex executive function tasks.
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