Evidence map›Paper›PMID 41716088›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2026

Influenza vaccine effectiveness from nine studies during drifted A(H3N2) subclade K predominance, Europe, September 2025 to January 2026.

Heloise Lucaccioni, Diogo Fp Marques, Freja Kirsebom, Hanne-Dorthe Emborg, Mark Hamilton, Heather Whitaker, Amanda Bolt Botnen, Magda Bucholc, Francisco Pozo, Nick Andrews and 11 more

Erratum issuedAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Population immunity, post-vaccine and post-infection antibody responses to influenza A (H3N2) subclade J.2 and K (J.2.4.1) viruses, Hong Kong, 2025.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Heloise LucaccioniEpiconcept, Paris, France.
Diogo Fp MarquesEpiconcept, Paris, France.
Freja KirsebomUK Health Security Agency, London, United Kingdom.
Hanne-Dorthe EmborgDepartment of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen Denmark.
Mark HamiltonPublic Health Scotland, Glasgow, United Kingdom.
Heather WhitakerUK Health Security Agency, London, United Kingdom.
Amanda Bolt BotnenDepartment of Virology and Microbiological Preparedness, Statens Serum Institut, Copenhagen, Denmark.
Magda BucholcPublic Health Agency, Belfast, United Kingdom.
Francisco PozoNational Centre for Microbiology, Institute of Health Carlos III, Madrid, Spain.
Nick AndrewsUK Health Security Agency, London, United Kingdom.
Ramona TrebbienDepartment of Virology and Microbiological Preparedness, Statens Serum Institut, Copenhagen, Denmark.
Safraj Shahul HameedPublic Health Scotland, Glasgow, United Kingdom.
Karina Lauenborg MøllerData Integration and Analyses, Statens Serum Institut, Copenhagen, Denmark.
Mark G O'DohertyPublic Health Agency, Belfast, United Kingdom.
Jamie Lopez-BernalUK Health Security Agency, London, United Kingdom.
Kirsty MorrisonPublic Health Scotland, Glasgow, United Kingdom.
Simon CottrellPublic Health Wales, Cardiff, United Kingdom.
Suzanne WiltonPublic Health Agency, Belfast, United Kingdom.
Angela Mc RoseEpiconcept, Paris, France.
Esther KisslingEpiconcept, Paris, France.
European IVE groupThe members of the network are listed under Collaborators.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The European 2025/26 influenza season is dominated by the influenza A(H3N2) virus, with most sequenced viruses belonging to subclade K, genetically drifted from the vaccine virus, raising concerns around vaccine effectiveness (VE). Despite this, VE estimates from nine European studies (19 countries) indicate all-age influenza A VE of 25-45% for outpatient and hospital settings combined, similar to other seasons, with highest estimates among children (47-72%). Vaccination should be encouraged and complemented by other infection prevention and control measures.

Indexed as

Influenza A Virus, H3N2 SubtypeInfluenza, HumanInfluenza VaccinesVaccine EfficacyChildChild, PreschoolEuropeHumansSeasonsVaccinationInfluenza VaccinesEuropeinfluenzamulticentre studytest-negative designvaccine effectiveness

Identifiers

PMID41716088
PMCPMC12924001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.