Evidence map›Paper›PMID 41715922›Full record

ArticleHGG advances2026

Genome-wide investigation of prosody perception: Shared genetic influences between speech rhythm, musical rhythm, and reading traits.

Alyssa C Scartozzi, Youjia Wang, Peyton L Coleman, Ximena León Du'Mottuchi, Tara L Henechowicz, Daniel E Gustavson, Lauren E Petty, Heather M Highland, Nicole Creanza, Cyrille L Magne and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in HGG advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Alyssa C ScartozziVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37203, USA. Electronic address: alyssa.c.scartozzi@vanderbilt.edu.
Youjia WangDepartment of Otolaryngology - Head & Neck Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Medical College of Wisconsin, Department of Internal Medicine and Pediatrics, Milwaukee, WI 53226, USA.
Peyton L ColemanVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37203, USA; Center for Digital Genomic Medicine, Vanderbilt University Medical Center, Nashville, TN 27203, USA.
Ximena León Du'MottuchiDepartment of Biological Sciences, Vanderbilt University, Nashville, TN 37203, USA.
Tara L HenechowiczInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO 80303, USA.
Daniel E GustavsonInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO 80303, USA.
Lauren E PettyVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37203, USA.
Heather M HighlandDepartment of Epidemiology, UTHealth Houston, Houston, TX 77030, USA.
Nicole CreanzaDepartment of Biological Sciences, Vanderbilt University, Nashville, TN 37203, USA.
Cyrille L MagneDepartment of Psychology, Middle Tennessee State University, Murfreesboro, TN 37132, USA.
Rosa S GísladóttirDepartment of Icelandic and Comparative Cultural Studies, University of Iceland, Saemundargata 2, 102 Reykjavik, Iceland.
Nancy J CoxVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37203, USA.
Jennifer E BelowVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37203, USA.
Srishti NayakVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37203, USA; Department of Otolaryngology - Head & Neck Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Psychology, Middle Tennessee State University, Murfreesboro, TN 37132, USA. Electronic address: srishti.nayak@vumc.org.
Reyna L GordonVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37203, USA; Department of Otolaryngology - Head & Neck Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

Funding

Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jeffrey L Neul · 2020 to 2026
$10.3M
Establishing if Music Engagement is a Protective Factor in Adolescent Substance Use Using Existing Longitudinal, Genetic, and Environmental DatasetsR01DA059804 · NIDA · UNIVERSITY OF COLORADO · PI Daniel Gustavson · 2024 to 2026
$2.0M
NICHD NIH HHS P50 HD103537NIDA NIH HHS R01 DA059804
6 · The paper itself

Abstract

Prosody perception is an often overlooked aspect of human language despite its importance in facilitating spoken language comprehension. Sensitivity to prosodic cues varies between individuals, and prosody perception skills are shown to be associated with various language- and reading-related outcomes. Despite the importance of prosody perception in human communication, its underlying biology is poorly understood. This study investigates the genetic architecture of prosody (speech rhythm) perception and explores its evolutionary roots. We conducted a GWAS of prosody (n = 1,501) as measured by scores on the Test of Prosody via Syllable Emphasis ("TOPsy"). GWAS results yielded 14 suggestive significant signals (p < 5.00 × 10

Indexed as

Genome-Wide Association StudyMusicReadingSpeechSpeech PerceptionAnimalsFemaleHumansMalePolymorphism, Single Nucleotidecomplex geneticsgenome-wide association studylanguageprosodyspeech rhythm perception

Identifiers

PMID41715922
PMCPMC13091348

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.