Evidence map›Paper›PMID 41715894›Full record

ArticleOrganic letters2026

Iron-Catalyzed Stereospecific Heterocycle N-Glycosylation with Glycal Epoxides.

Xiao-Wen Zhang, Dakang Zhang, Zixiang Jiang, Hao Xu

Abstract read
In one paragraph

Article in Organic letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Xiao-Wen ZhangDepartment of Chemistry, Brandeis University, 415 South Street, Waltham, Massachusetts 02453, United States.
Dakang ZhangDepartment of Chemistry, Brandeis University, 415 South Street, Waltham, Massachusetts 02453, United States.ORCID 0009-0005-9149-189X
Zixiang JiangDepartment of Chemistry, Brandeis University, 415 South Street, Waltham, Massachusetts 02453, United States.ORCID 0009-0007-8265-6212
Hao XuDepartment of Chemistry, Brandeis University, 415 South Street, Waltham, Massachusetts 02453, United States.ORCID 0000-0001-5029-8392

Funding

Selective Nitrogen Atom Transfer for Applications in Biomedical SciencesR35GM134926 · NIGMS · BRANDEIS UNIVERSITY · PI XU, HAO · 2020 to 2025
$2.1M
A 400 MHz NMR SpectrometerS10OD034395 · OD · BRANDEIS UNIVERSITY · PI KRAUSS, ISAAC JONATHAN · 2023 to 2023
$482k
NIGMS NIH HHS R35 GM134926NIH HHS S10 OD034395
6 · The paper itself

Abstract

Stereospecific N-glycosylation of heterocycles with glycal epoxides could readily provide valuable building blocks for drug discovery, but heterocycle N-glycosylation with a pyranose-based glycal epoxide is still difficult using existing methods. We report herein an iron-catalyzed stereospecific heterocycle N-glycosylation method for these glycal epoxides in high yields with low catalyst loadings. This method is functional-group-tolerant and effective for a wide variety of functionalized, complex glycal epoxides and heterocycles.

Identifiers

PMID41715894
PMCPMC12949690

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.