ReviewCost effectiveness and resource allocation : C/E2026
Willingness to pay for a quality-adjusted life year in Iran: a systematic review.
Review in Cost effectiveness and resource allocation : C/E, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe monetary value assigned to a quality-adjusted life year (QALY) serves as a fundamental threshold in cost-effectiveness evaluations, contributing to informing resource allocation decisions within healthcare systems given the more severe resource constraints. The present study aims to conduct a systematic review of the existing literature in terms of the methodologies employed, estimated values, and key determinants affecting willingness to pay per QALY in the context of Iran.
methodsWe undertook a systematic review of the published work on willingness to pay (WTP) per QALY by searching eight international and national databases from inception of databases to March 2025, including PubMed, Embase, Web of Science, Scopus, Iran Medex, SID, Magiran, and the Barkat Knowledge Network system. NIH quality assessment tool was used for quality appraisal.
resultsThe search yielded in 517 articles. After screening, seven articles were eligible. The findings showed that the range of WTP per QALY in Iran is very wide, varying from $1,032 (0.22 times GDP per capita) for neck and back pain interventions to $14,173 (1.98 times GDP per capita) for cancer interventions. The median of WTP/QALY was 0.4 of GDP per capita and was roughly $1921 per QALY, substantially lower than the WHO’s recommended threshold. Education, income, employment, marital status, being head of household, age, gender, were the most important determinants of WTP among all included studies.
conclusionCurrent WTP/QALY estimates fall substantially below WHO thresholds, suggesting the need to revise Iran’s cost-effectiveness threshold framework. However, further studies are needed and future research should aim to minimize bias in WTP estimates and decision-making criteria to enhance the resource allocation process.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.