Evidence map›Paper›PMID 41714891›Full record

ArticleThe world journal of men's health2026

ETS Homologous Factor Drives Endothelial Dysfunction in Diabetes-Related Erectile Dysfunction

Chunhui Liu, Ning Liu, Zonghao You, Shuqiu Chen, Jianping Wu, Jia Zhao, Ming Chen, Shenghui Liang, Chao Sun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The world journal of men's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chunhui LiuDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, China.ORCID https://orcid.org/0000-0003-0231-6271
Ning LiuDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, China.ORCID https://orcid.org/0009-0003-1120-5335
Zonghao YouDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, China.ORCID https://orcid.org/0000-0003-4807-9750
Shuqiu ChenDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, China.ORCID https://orcid.org/0000-0003-4117-1917
Jianping WuDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, China.ORCID https://orcid.org/0000-0002-1860-0608
Jia ZhaoLife Sciences Institute, Departments of Cellular & Physiological Sciences and Surgery, The University of British Columbia, Vancouver, BC, Canada.ORCID https://orcid.org/0000-0001-5555-8042
Ming ChenDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, China.ORCID https://orcid.org/0000-0002-3572-6886
Shenghui LiangLife Sciences Institute, Departments of Cellular & Physiological Sciences and Surgery, The University of British Columbia, Vancouver, BC, Canada. shenghui.liang@ubc.ca.ORCID https://orcid.org/0000-0002-3698-3390
Chao SunDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, China.ORCID https://orcid.org/0000-0003-0538-1239

Funding

China Postdoctoral Science Foundation 2024M750457Zhongda Hospital Affiliated to Southeast University, Jiangsu Province High-Level Hospital Construction Funds GSP-ZXY12
6 · The paper itself

Abstract

purposeDiabetes mellitus (DM)-related erectile dysfunction (DMED), a prevalent complication of diabetes, is closely associated with endothelial dysfunction. This study investigated the role of E26 transformation-specific homologous factor (Ehf) in mediating endothelial dysfunction in DMED and explored its downstream molecular mechanisms. MATERIALS AND

methodsRat corpus cavernosum endothelial cells (CCECs) were cultured under high glucose (HG) conditions to simulate a diabetic environment

results

conclusions

Indexed as

AutophagyEndothelium, vascularErectile dysfunctionNitric oxide synthase type IIITranscription factorUbiquitination

Identifiers

PMID41714891
PMCPMC13646319

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.