Evidence map›Paper›PMID 41714832›Full record

ArticleAnnals of surgical oncology2026

Patient-Reported Symptom Recovery After Upper Gastrointestinal Cancer Surgery: A Prospective Study Using the MDASI-UGI-Surg.

Koichi Tomita, Paula M Smith, Maho Takayama, Cong Pan, Shu-En Shen, Xuemei Wang, Xin Shelley Wang, Loretta A Williams, Elsa M Arvide, Connie To and 18 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Koichi TomitaDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Paula M SmithDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Maho TakayamaDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Cong PanDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Shu-En ShenDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Xuemei WangDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Xin Shelley WangDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Loretta A WilliamsDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Elsa M ArvideDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Connie ToDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Ravi RajaramDepartment of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Kyle G MitchellDepartment of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
David C RiceDepartment of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Wayne L HofstetterDepartment of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Mara B AntonoffDepartment of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Reza J MehranDepartment of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Ara J VaporciyanDepartment of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Garrett L WalshDepartment of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Jessica E MaxwellDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Rebecca A SnyderDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Michael P KimDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Ching-Wei D TzengDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Paul F MansfieldDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Stephen G SwisherDepartment of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Jeffrey E LeeDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Brian D BadgwellDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Matthew H G KatzDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Naruhiko IkomaDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. nikoma@mdanderson.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnderstanding patients' symptom recovery after upper gastrointestinal (UGI) cancer surgery is essential for patient-centered care, yet detailed longitudinal patient-reported outcome data remain limited. We conducted a prospective study using the novel MD Anderson Symptom Inventory for UGI Surgery (MDASI-UGI-Surg) tool.

methodsPatients undergoing esophageal (n = 42), gastric (n = 27), or pancreatic (n = 74) cancer surgery from February to September 2024 were enrolled. The MDASI-UGI-Surg comprises 22 symptoms and 6 interference items. The five most severe symptoms and three most severe interference items on postoperative day (POD) 3 were identified. Recovery was defined as achieving mild severity for both symptom and interference composites. Multivariable analysis was performed to identify factors associated with recovery at postoperative month (POM) 1.

resultsMost symptoms peaked at POD3. The five most severe symptoms were pain, fatigue, sleep disturbance, drowsiness, and dry mouth; the top three interference items were general activity, working, and enjoyment of life. Symptom recovery followed three phases: an acute improvement phase (POD3-14), a plateau phase (POD14-POM1), and a persistent recovery phase extending to POM6. Symptom profiles were similar across organ groups, and fatigue remained prolonged. Cumulative recovery rates were 64.8% at POM1, 78.9% at POM3, and 90.8% at POM6. Postoperative complications and readmissions were associated with delayed recovery at POM1, and the type of surgery predicted recovery in multivariable models.

conclusionsThis study provides a detailed characterization of symptom recovery after UGI cancer surgery. These findings support improved preoperative counseling and postoperative care planning.

Indexed as

Digestive System Surgical ProceduresEsophageal NeoplasmsGastrointestinal NeoplasmsPatient Reported Outcome MeasuresPostoperative ComplicationsQuality of LifeRecovery of FunctionAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisProspective StudiesSymptom BurdenCumulative Recovery RateMD Anderson Symptom Inventory (MDASI)Patient-Reported Outcomes (PROs)Postoperative Symptom BurdenProspective Cohort StudyUpper Gastrointestinal (UGI) Cancer Surgery

Identifiers

PMID41714832
PMCPMC13179234

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.