Evidence map›Paper›PMID 41714825›Full record

ArticleJournal of patient-reported outcomes2026

Validity and reliability testing of the Thai version of the emPHasis-10 questionnaire for patients with pulmonary arterial hypertension.

Sahachat Aueyingsak, Kanokporn Khankaew, Wimolporn Teerawattananant, Parinyaporn Singsangtam, Aroonsri Sanmueang, Montri Yasud, Nichamon Ekphaphan, Burabha Pussadhamma

Abstract readValidation Study
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Article in Journal of patient-reported outcomes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Sahachat AueyingsakDepartment of Physical Therapy, College of Health Sciences, Christian University of Thailand, Nakhon Pathom, Nakhon Pathom Province, Thailand.ORCID http://orcid.org/0000-0002-5761-149X
Kanokporn KhankaewQueen Sirikit Heart Center of the Northeast, Faculty of Medicine, Khon Kaen University, Khon Kaen Province, Thailand.ORCID http://orcid.org/0000-0002-1839-9959
Wimolporn TeerawattananantQueen Sirikit Heart Center of the Northeast, Faculty of Medicine, Khon Kaen University, Khon Kaen Province, Thailand.ORCID http://orcid.org/0009-0007-0937-2977
Parinyaporn SingsangtamQueen Sirikit Heart Center of the Northeast, Faculty of Medicine, Khon Kaen University, Khon Kaen Province, Thailand.ORCID http://orcid.org/0000-0001-9397-1073
Aroonsri SanmueangQueen Sirikit Heart Center of the Northeast, Faculty of Medicine, Khon Kaen University, Khon Kaen Province, Thailand.ORCID http://orcid.org/0009-0007-3943-3312
Montri YasudQueen Sirikit Heart Center of the Northeast, Faculty of Medicine, Khon Kaen University, Khon Kaen Province, Thailand.ORCID http://orcid.org/0009-0002-5120-6909
Nichamon EkphaphanQueen Sirikit Heart Center of the Northeast, Faculty of Medicine, Khon Kaen University, Khon Kaen Province, Thailand.ORCID http://orcid.org/0009-0007-6290-213X
Burabha PussadhammaDepartment of Medicine, Faculty of Medicine, Khon Kaen University, Khon, Kaen Province, Thailand. pussadhamma@gmail.com.ORCID http://orcid.org/0000-0002-9688-823X

Funding

the Esan Heart and Lung Research Group, Faculty of Medicine, Khon Kaen University the Esan Heart and Lung Research Group, Faculty of Medicine, Khon Kaen University
6 · The paper itself

Abstract

backgroundThe emPHasis-10 questionnaire is a specific tool for assessing health-related quality of life (HRQoL) in pulmonary arterial hypertension (PAH). We conducted the cross-cultural validation of the Thai emPHasis-10 questionnaire with an assessment of its validity and reliability in patients with PAH.

methodsThe original English emPHasis-10 questionnaire was translated into Thai using a forward and backward translation process. Content validity was assessed by five experts using the Item-Objective Congruence (IOC) index, and reliability was assessed by 20 patients with PAH using Cronbach’s alpha for internal consistency and the intraclass correlation coefficient (ICC) for test-retest reliability. All patients had a confirmed diagnosis of PAH by right heart catheterization, and baseline clinical and hemodynamic characteristics were collected.

resultsFor Thai emPHasis-10 questionnaire, the IOC value was 0.94 (range 0.80 to 1.00). Among all patients, 19 (95%) were female, and the mean age±standard deviation (SD) was 46.8 ± 14.2 years, and 17 (85%) were at World Health Organization functional class II. Idiopathic PAH, PAH associated with connective tissue disease, and PAH associated with congenital heart disease were classified in 7, 6, and 7 patients, respectively. The mean baseline mean pulmonary arterial pressure and pulmonary vascular resistance were 55.1 ± 19.5 mmHg and 13.1 ± 8.4 Wood units, respectively. The mean ± SD of the Thai emPHasis-10 score was 18 ± 10. Cronbach’s alpha and ICC values were 0.925 and 0.996 (95% confidence interval 0.991 to 0.999), respectively.

conclusionThe Thai emPHasis-10 questionnaire has acceptable validity and reliability. This tool can be used as an additional measure for PAH severity assessment.

Indexed as

Hypertension, PulmonaryPulmonary Arterial HypertensionQuality of LifeAdultFemaleHumansMaleMiddle AgedReproducibility of ResultsSurveys and QuestionnairesThailandTranslationsemPHasis-10 questionnairePulmonary arterial hypertensionPulmonary hypertensionQuality of lifeThai

Identifiers

PMID41714825
PMCPMC12923680

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