Evidence map›Paper›PMID 41714815›Full record

ArticleNature microbiology2026

Conserved CD4

Jessica Braverman, Ian R Monk, Adrianna M Turner, Asolina Braun, Heran Zhang, Shanzou Chung, Claerwen M Jones, Pirooz Zareie, Nicole L La Gruta, Joanne Rimmer and 6 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jessica BravermanDepartment of Microbiology and Immunology, The University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Ian R MonkDepartment of Microbiology and Immunology, The University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0001-6982-8074
Adrianna M TurnerDepartment of Microbiology and Immunology, The University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Asolina BraunDepartment of Biochemistry and Molecular Biology, Immunity Program, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia.
Heran ZhangDepartment of Microbiology and Immunology, The University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Shanzou ChungDepartment of Biochemistry and Molecular Biology, Immunity Program, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia.
Claerwen M JonesDepartment of Biochemistry and Molecular Biology, Immunity Program, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia.
Pirooz ZareieDepartment of Microbiology and Immunology, The University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Nicole L La GrutaDepartment of Biochemistry and Molecular Biology, Immunity Program, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia.
Joanne RimmerDepartment of Otolaryngology Head & Neck Surgery, Monash Health, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0003-0533-8265
Glen P CarterDepartment of Microbiology and Immunology, The University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0002-7306-9362
Benjamin P HowdenDepartment of Microbiology and Immunology, The University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0003-0237-1473
Nancy WangDepartment of Microbiology and Immunology, The University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Anthony W PurcellDepartment of Biochemistry and Molecular Biology, Immunity Program, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0003-0532-8331
Timothy P StinearDepartment of Microbiology and Immunology, The University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0003-0150-123X
Linda M WakimDepartment of Microbiology and Immunology, The University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia. wakiml@unimelb.edu.au.ORCID http://orcid.org/0000-0003-1752-9579

Funding

Department of Health | National Health and Medical Research Council (NHMRC) 2000512
6 · The paper itself

Abstract

Vaccines are effective and much-needed tools against bacterial infection, which mitigate multidrug resistance; however, selection of bacterial antigens that elicit protection and contribute to effective vaccines remains challenging. Here we use immunopeptidomics to identify CD4

Indexed as

CD4-Positive T-LymphocytesEpitopes, T-LymphocyteStaphylococcal VaccinesStreptococcal VaccinesStreptococcusAnimalsAntigens, BacterialBacterial ProteinsFemaleHumansMethicillin-Resistant Staphylococcus aureusMiceStaphylococcal InfectionsStaphylococcus aureusStreptococcal InfectionsStreptococcus pneumoniaeAntigens, BacterialBacterial ProteinsEpitopes, T-LymphocyteStaphylococcal VaccinesStreptococcal Vaccines

Identifiers

PMID41714815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.