Evidence map›Paper›PMID 41714736›Full record

ArticleScientific reports2026

Inhibitory effect of the methanol extract of Clerodendrum volubile Linn. on carbon tetrachloride-induced early hepatic fibrogenesis: in silico and in vivo study.

Ifeoluwa Temitayo Oyeyemi, Abiola Mojisola Asowata-Ayodele, Ademola Oluwatobiloba Adetula, Kabirat Adedunmola Sulaiman, Demilade Elizabeth Omape, Muyiwa Samuel Fageyinbo

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ifeoluwa Temitayo OyeyemiDepartment of Biosciences and Biotechnology, University of Medical Sciences, Ondo, Nigeria. ioyeyemi@unimed.edu.ng.ORCID http://orcid.org/0000-0002-2374-506X
Abiola Mojisola Asowata-AyodeleDepartment of Biosciences and Biotechnology, University of Medical Sciences, Ondo, Nigeria.ORCID http://orcid.org/0000-0002-9531-1105
Ademola Oluwatobiloba AdetulaDepartment of Biosciences and Biotechnology, University of Medical Sciences, Ondo, Nigeria.
Kabirat Adedunmola SulaimanDepartment of Science Laboratory Technology, University of Medical Sciences, Ondo, Nigeria.ORCID http://orcid.org/0000-0003-1895-8033
Demilade Elizabeth OmapeDepartment of Biosciences and Biotechnology, University of Medical Sciences, Ondo, Nigeria.
Muyiwa Samuel FageyinboDepartment of Pharmacology and Therapeutics, University of Medical Sciences, Ondo, Nigeria.ORCID http://orcid.org/0000-0002-0258-8499

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver disease remains a significant public health problem, claiming several lives globally every year. All forms of liver disease, irrespective of the cause, lead to liver fibrosis if they persist. Liver fibrosis ends up in liver cirrhosis and creates a microenvironment that enhances the development of hepatocellular carcinoma. Clerodendrum volubile is a food and medicinal plant consumed to manage several diseases, including liver diseases. Liver fibrosis was induced in Wistar rats with carbon tetrachloride (CCl

Indexed as

ClerodendrumLiver CirrhosisPlant ExtractsAnimalsAntioxidantsCarbon TetrachlorideCytochrome P-450 CYP2E1Lipid PeroxidationLiverMaleMethanolOxidative StressRatsRats, WistarAntioxidantsCarbon TetrachlorideCytochrome P-450 CYP2E1MethanolPlant ExtractsClerodendrum volubileCytochrome 450 2E1FibrogenesisOxidative stress

Identifiers

PMID41714736
PMCPMC13018557

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.