Evidence map›Paper›PMID 41714533›Full record

ArticleParasitology research2026

The Toxoplasma gondii prevalence and its impact on tick-borne encephalitis virus infection among humans in Heilongjiang province of China.

Wanting Li, Lu Zhang, Wei Wang, Weiyan Yin, Feiluran Maimaiti, Mengru Zhao, Xiaohong Peng, Wenzhong Wu, Shouxu Lv, Zhijun Hou

Abstract read
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In one paragraph

Article in Parasitology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wanting Li *Tick-Borne Diseases Research and Therapeutic Center, Heilongjiang Red Cross Sengong General Hospital, Harbin, China.
Lu Zhang *Laboratory of vector-borne diseases and pathogens ecology, College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, China.
Wei WangTick-Borne Diseases Research and Therapeutic Center, Heilongjiang Red Cross Sengong General Hospital, Harbin, China.
Weiyan YinLaboratory of vector-borne diseases and pathogens ecology, College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, China.
Feiluran MaimaitiLaboratory of vector-borne diseases and pathogens ecology, College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, China.
Mengru ZhaoLaboratory of vector-borne diseases and pathogens ecology, College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, China.
Xiaohong PengTick-Borne Diseases Research and Therapeutic Center, Heilongjiang Red Cross Sengong General Hospital, Harbin, China.
Wenzhong WuTick-Borne Diseases Research and Therapeutic Center, Heilongjiang Red Cross Sengong General Hospital, Harbin, China.
Shouxu LvTick-Borne Diseases Research and Therapeutic Center, Heilongjiang Red Cross Sengong General Hospital, Harbin, China.
Zhijun HouLaboratory of vector-borne diseases and pathogens ecology, College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, China. houzhijundb@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxoplasmosis and tick-borne encephalitis (TBE) are endemic in Heilongjiang province, China, posing a significant threat to public health. Although some research has indicated that Toxoplasma gondii infection may suppress the host’s immune response and increase susceptibility to other pathogens, no studies have been conducted to explore the association between these two diseases. From 2020 to 2023, a total of 415 serum samples were collected and tested for both T. gondii and tick-borne encephalitis virus (TBEV) infections using enzyme-linked immunosorbent assay (ELISA) by us. The positive rates of T. gondii and tick-borne encephalitis virus were 14.15% (60/415) and 36.14% (150/415), respectively. The positive rate of tick-borne encephalitis virus was 66.67% (40/60) in T. gondii-positive patients, while it was 30.99% (110/355) in the group of T. gondii-negative patients. A statistically significant correlation was observed between T. gondii infection and the tick-borne encephalitis virus (TBEV) positive status (P < 0.05). Age and occupation were significantly associated with seropositivity of T. gondii (P < 0.05). This finding provides the first indication that individuals infected with T. gondii are more susceptible to tick-borne encephalitis virus (TBEV).

Indexed as

Encephalitis, Tick-BorneToxoplasmosisAdolescentAdultAgedAntibodies, ProtozoanAntibodies, ViralChildChild, PreschoolChinaEncephalitis Viruses, Tick-BorneEnzyme-Linked Immunosorbent AssayFemaleHumansMaleMiddle AgedAntibodies, ProtozoanAntibodies, ViralELISARisk factorsTick-borne encephalitis virusToxoplasma gondii

Identifiers

PMID41714533
PMCPMC12920383

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.