Evidence map›Paper›PMID 41714525›Full record

ArticleEuropean geriatric medicine2026

Association of respiratory function with sarcopenia in older outpatients: cross-sectional analysis of baseline data from the JUSTICE-TOKYO prospective cohort study.

Kenya Kanematsu, Kei Matsuno, Aya Shimamoto, Ayako Nakamura, Riko Fujioka, Koji Sugano, Daisuke Asaoka, Katsumi Miyauchi

Abstract read
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Article in European geriatric medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kenya KanematsuDepartment of Clinical Laboratory, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, Japan.
Kei MatsunoDepartment of Respiratory Medicine, Juntendo Tokyo Koto Geriatric Medical Center, 3-3-20 Shinsuna, Koto-Ku, Tokyo, 136-0075, Japan. kmatsuno@juntendo.ac.jp.ORCID http://orcid.org/0009-0007-7536-0763
Aya ShimamotoDepartment of Clinical Laboratory, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, Japan.
Ayako NakamuraDepartment of Clinical Laboratory, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, Japan.
Riko FujiokaDepartment of Respiratory Medicine, Juntendo Tokyo Koto Geriatric Medical Center, 3-3-20 Shinsuna, Koto-Ku, Tokyo, 136-0075, Japan.
Koji SuganoDepartment of Respiratory Medicine, Juntendo Tokyo Koto Geriatric Medical Center, 3-3-20 Shinsuna, Koto-Ku, Tokyo, 136-0075, Japan.
Daisuke AsaokaDepartment of Gastroenterology, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, Japan.
Katsumi MiyauchiDepartment of Cardiology, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, Japan.

Funding

JSPS KAKENHI JP16K09042JSPS KAKENHI JP21K11633
6 · The paper itself

Abstract

purposeSarcopenia, characterized by loss of muscle mass and function, can affect the respiratory muscles and impair pulmonary function. However, evidence on the association between sarcopenia and respiratory function in older adults remains limited. This study examined the relationships among outpatients attending a hospital for older adult medicine.

methodsBaseline data from 810 outpatients aged ≥ 65 in the JUSTICE-TOKYO study were analyzed. Individuals with asthma, chronic obstructive pulmonary disease, or interstitial lung disease were excluded. The mean age was 78.2 ± 6.1 years, and 341 (42.1%) were male Sarcopenia was diagnosed based on 2019 Asian Working Group for Sarcopenia criteria. Pulmonary function measures included vital capacity (% predicted), forced expiratory volume in one second (% predicted), FEV1/FVC ratio, and peak expiratory flow rate (PEFR). Receiver operating characteristic (ROC) curve analyses were performed to assess the diagnostic performance of VC (% predicted) and PEFR for sarcopenia.

resultsSarcopenia was identified in 170 patients (21%; 102 men,68 women). Patients had a higher prevalence of myocardial infarction, heart failure, and malignancies. ROC curve analyses showed that VC (% predicted) had an optimal cutoff of 94.2% (sensitivity:0.653, specificity:0.613), and area under the curve(AUC) of 0.66. The diagnostic performance of VC (% predicted) was comparable to PEFR (AUC: 0.70 in men and 0.69 in women).

conclusionRespiratory function, particularly VC (% predicted), was significantly associated with sarcopenia in older adult outpatients. VC (% predicted) demonstrates diagnostic performance comparable to PEFR and may serve as a practical parameter for sarcopenia risk identification in clinical practice.

Indexed as

SarcopeniaAgedAged, 80 and overCross-Sectional StudiesFemaleForced Expiratory VolumeHumansJapanMaleOutpatientsPeak Expiratory Flow RateProspective StudiesRespiratory Function TestsRespiratory MusclesROC CurveVital CapacityJapanOlder outpatientsPeak expiratory flow rateRespiratory functionSarcopeniaVital capacity (% predicted)

Identifiers

PMID41714525

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