Evidence map›Paper›PMID 41714464›Full record

ArticleJournal of natural medicines2026

Xylocargranosides A‒B and Xylocargranin a from the Mangrove Xylocarpus granatum.

Nguyen Phuong Thao, Tran Thi Bich Ha, Kieu Thi Phuong Linh, Pham Thi Mai Huong, Pham Thanh Binh, Vu Thanh Trung, Nguyen The Cuong, Tran Viet Hung, Nguyen Van Thanh

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Article in Journal of natural medicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nguyen Phuong ThaoInstitute of Chemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam.
Tran Thi Bich HaGraduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam. bichha.vknt@gmail.com.
Kieu Thi Phuong LinhInstitute of Chemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam.
Pham Thi Mai HuongInstitute of Medicine and Pharmacy, Thanh Do University, Kim Chung, Hoai Duc, Hanoi, Vietnam.
Pham Thanh BinhInstitute of Chemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam.
Vu Thanh TrungInstitute of Chemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam.
Nguyen The CuongInstitute of Biology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam.
Tran Viet HungGraduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam.
Nguyen Van ThanhInstitute of Chemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam. nvthanh1977@ich.vast.vn.

Funding

National Foundation for Science and Technology Development 104.01-2021.02
6 · The paper itself

Abstract

Xylocargranosides A–B (1–2) and xylocargranin A (3), three previously undescribed compounds, along with twelve known metabolites (4–15), were isolated from the leaves of Xylocarpus granatum. The structures and absolute configurations of the new compounds were elucidated through detailed analyses of HRESIMS and NMR spectra, corroborated by quantum chemical calculations of NMR chemical shifts and ECD spectra. Notably, compound 1 was identified as a rare 25,26,27-trinor-apotirucallane-type triterpenoid glucoside, distinguished by an uncommon side chain forming a δ-lactone moiety. The cytotoxic activities of all isolated compounds were evaluated against the A549, MCF7, and HepG2 cell lines.

Indexed as

Antineoplastic Agents, PhytogenicMeliaceaePlant ExtractsTriterpenesA549 CellsCell Line, TumorHep G2 CellsHumansMagnetic Resonance SpectroscopyMCF-7 CellsMolecular StructurePlant LeavesAntineoplastic Agents, PhytogenicPlant ExtractsTriterpenesCytotoxicityFlavonoidMeliaceaeTrinor-apotirucallaneXylocargraninXylocargranosideXylocarpus granatum

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.