Evidence map›Paper›PMID 41714340›Full record

ArticleScientific reports2026

Association between prenatal exposure to residential pyrethroid insecticides and congenital hypothyroidism using propensity score matching.

Asieh Heidari, Afshin Ebrahimi, Mahmoud Mirkhalafzadeh, Mahin Hashemipour, Mohammad Reza Maracy

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Asieh HeidariEnvironment Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID https://orcid.org/0000-0002-1018-3766
Afshin EbrahimiEnvironment Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID https://orcid.org/0000-0002-3640-087X
Mahmoud MirkhalafzadehDepartment of Information Technology, Health Information Technology, Health Vice-Chancellery, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID https://orcid.org/0009-0009-2360-2139
Mahin HashemipourMetabolic Liver Disease Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. mahin.hashemipour@gmail.com.ORCID https://orcid.org/0000-0002-6032-5523
Mohammad Reza MaracyEnvironment Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran. mrmaracy@yahoo.co.uk.ORCID https://orcid.org/0000-0002-3695-0863

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to assess the relationship between exposure to Type II pyrethroids and congenital hypothyroidism (CH), particularly in leishmaniasis-endemic regions where the immunity of residents is compromised.In this population-based case-control study, we used all mothers and newborns secondary data for the period 2017-2022 in eastern Isfahan province. Cases were newborns confirmed with diagnosis of CH. Data of insecticides spraying and fogging facilitated the identification of affected and unaffected regions. Propensity score (PS) matching was applied for matching controls to cases (5:1). The descriptive information reported along with the mapping generated using ArcGIS 10.8.2. Trimester-Specific analyses were conducted using STATA 17 with adjusting for possible confounders.After PS matching, out of 37,085 mother-newborn pairs registered in national Integrated Health System, 744 were included in the final analysis. After adjustment for birth and maternal characteristics, the association strengthened for second-trimester exposure (OR

Indexed as

Congenital HypothyroidismInsecticidesMaternal ExposurePrenatal Exposure Delayed EffectsPyrethrinsAdultCase-Control StudiesFemaleHumansInfant, NewbornIranMalePregnancyPropensity ScoreInsecticidesPyrethrinsCongenital hypothyroidismInsecticidesPrenatalPyrethroidResidential

Identifiers

PMID41714340
PMCPMC13018311

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.