ArticleKorean circulation journal2026
Prognostic Impact of 1-Year Left Ventricular Mass Regression After Aortic Valve Surgery in Severe Aortic Regurgitation.
Article in Korean circulation journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Postoperative Reverse Remodeling in Aortic Regurgitation: What One-Year Left Ventricular Mass Regression Tells Us.Korean circulation journal · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesLeft ventricular reverse remodeling (LVRR) following aortic valve surgery has been associated with improved outcomes in chronic aortic regurgitation (AR), yet its definition remains controversial. This study evaluated the prognostic impact of LVRR using the degree of left ventricular mass index (LVMi) reduction.
methodsWe retrospectively analyzed patients undergoing surgery for severe AR at Asan Medical Center between January 2006 and December 2020. LVRR was determined by the degree of LVMi regression at 1 year postoperatively. Patients were categorized into greater (n=315) or lesser (n=248) regression groups based on time-dependent receiver operating characteristic curve analysis. The primary endpoint was a composite of all-cause mortality and rehospitalization due to heart failure (HF).
resultsOver a median follow-up of 7.58 years, 29 patients (9.2%) in the greater regression group and 51 (20.6%) in the lesser regression group experienced the primary endpoint. Multivariate Cox regression analysis revealed that the greater regression group had a lower risk of mortality or HF rehospitalization (hazard ratio, 0.44; 95% confidence interval, 0.27-0.72). Further analyses identified hypertension as the only clinical predictor of reduced LVRR, while smaller left atrial diameter, larger baseline LVMi, and higher left ventricular ejection fraction were independent echocardiographic predictors of greater LVRR.
conclusionsGreater 1-year postoperative LVMi regression was associated with improved outcomes in chronic AR, particularly by reducing HF-related hospitalizations. While hypertension negatively affected remodeling, favorable baseline echocardiographic profiles, including higher LVMi, preserved left ventricular ejection fraction, and a smaller left atrium, were connected to more significant postoperative LVRR.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.