Evidence map›Paper›PMID 41713203›Full record

ArticleSleep medicine2026

Sleep physiology associated with cognitive disengagement syndrome in adolescents with and without ADHD.

Jessica R Lunsford-Avery, Andrew D Krystal, Melissa C Miller, Stephen P Becker

Abstract read
In one paragraph

Article in Sleep medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jessica R Lunsford-AveryDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, 2400 Pratt Street, 7th Floor, Durham, NC, 27705, USA. Electronic address: jessica.r.avery@duke.edu.
Andrew D KrystalDepartment of Psychiatry and Behavioral Sciences, University of California School of Medicine, 675 18th Street, #5328, San Francisco, CA, 94107, USA. Electronic address: Andrew.krystal@ucsf.edu.
Melissa C MillerDivision of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 10006, Cincinnati, OH, 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA. Electronic address: melissa.miller2@cchmc.org.
Stephen P BeckerDivision of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 10006, Cincinnati, OH, 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA. Electronic address: stephen.becker@cchmc.org.

Funding

Advancing Identification of Circadian Delay in ADHD Youth: Associations with Clinical Heterogeneity and CognitionR01MH136425 · NIMH · DUKE UNIVERSITY · PI Jessica Ruth Lunsford-Avery · 2025 to 2026
$1.5M
Sleep Dysfunction and Neurocognitive Outcomes in Adolescent ADHDK23MH108704 · NIMH · DUKE UNIVERSITY · PI LUNSFORD-AVERY, JESSICA RUTH · 2016 to 2022
$837k
Sustainable Habits for Encouraging Even Teen Sleep (SHEETS): A Digital Intervention to Enhance Sleep Regularity and Psychiatric Health in AdolescentsR34MH128440 · NIMH · DUKE UNIVERSITY · PI DUKE, NAOMI N, LUNSFORD-AVERY, JESSICA RUTH · 2022 to 2024
$725k
Preschool Attention and Sleep Support (PASS): A Telehealth Intervention for Children at Risk for ADHDR34MH131994 · NIMH · DUKE UNIVERSITY · PI LUNSFORD-AVERY, JESSICA RUTH · 2023 to 2025
$688k
NIMH NIH HHS K23 MH108704NIMH NIH HHS R01 MH136425NIMH NIH HHS R34 MH128440NIMH NIH HHS R34 MH131994
6 · The paper itself

Abstract

objectiveCognitive disengagement syndrome (CDS) is an attentional phenotype characterized by excessive daydreaming and hypoactivity that is distinct from attention-deficit/hyperactivity disorder (ADHD). Emerging research finds poorer sleep functioning to be associated with CDS symptoms, though few studies have used objective sleep methods such as polysomnography (PSG). This multi-informant, multi-method study examines whether PSG-assessed sleep physiology indices and subjective sleep quality/circadian preference are associated with CDS severity in adolescents with and without ADHD.

methodsParticipants were 62 medication-free adolescents (ages 13-17, 50% female), half with ADHD and half were non-psychiatric controls. Adolescents completed 3 consecutive nights of ambulatory PSG and measures of sleep quality and circadian preference. Parents completed measures of CDS and ADHD severity. Partial Pearson correlations covarying for age, sex, and pubertal status examined sleep physiology, sleep quality, and circadian preference in relation to CDS. Linear regressions explored whether associations differed by group.

resultsAdolescents with ADHD displayed greater CDS severity than controls. Longer PSG-measured latency to persistent sleep, greater wake after sleep onset and percentage of stage 1 (N1) sleep, and reduced sleep efficiency and total sleep time were associated with greater CDS severity. Poorer subjective sleep quality and greater eveningness were also associated with greater CDS severity. Findings were largely unchanged in sensitivity analyses controlling for ADHD severity. Associations between sleep and CDS did not differ between adolescents with ADHD compared to non-psychiatric controls.

conclusionAlthough adolescents with ADHD exhibited greater CDS severity than controls, PSG-assessed sleep physiology indices were associated with greater parent-reported CDS symptoms irrespective of diagnostic group. Longitudinal and experimental research is needed to replicate and extend findings.

Indexed as

Attention Deficit Disorder with HyperactivityCognitionSleepSleep QualityAdolescentCircadian RhythmFemaleHumansMalePolysomnographySeverity of Illness IndexSleep DurationSyndromeADHDAdolescentsCognitive disengagement syndromePolysomnographySleep physiologySluggish cognitive tempo

Identifiers

PMID41713203
PMCPMC12959369

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.