Evidence map›Paper›PMID 41712870›Full record

ArticleJCO precision oncology2026

Prognostic Implications of Codon-Specific

Sara Raji, Hamed Zaribafzadeh, Tyler Jones, Elishama Kanu, Kunling Tong, Ashley Fletcher, T Clark Howell, Shannon J McCall, Jeffrey R Marks, Bruce Rogers and 4 more

Abstract read
In one paragraph

Article in JCO precision oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Sara RajiDepartment of Surgery, Duke University School of Medicine, Durham, NC.ORCID 0000-0001-9084-3316
Hamed ZaribafzadehDepartment of Surgery, Duke University School of Medicine, Durham, NC.
Tyler JonesDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC.ORCID 0009-0005-0313-6282
Elishama KanuDepartment of Surgery, Duke University School of Medicine, Durham, NC.
Kunling TongDepartment of Surgery, Duke University School of Medicine, Durham, NC.ORCID 0009-0001-2413-6805
Ashley FletcherDepartment of Surgery, Duke University School of Medicine, Durham, NC.ORCID 0000-0003-2626-4867
T Clark HowellDepartment of Surgery, Duke University School of Medicine, Durham, NC.ORCID 0000-0002-7916-1952
Shannon J McCallDepartment of Pathology, Duke University School of Medicine, Durham, NC.ORCID 0000-0003-3957-061X
Jeffrey R MarksDepartment of Surgery, Duke University School of Medicine, Durham, NC.ORCID 0000-0002-2054-5468
Bruce RogersDepartment of Surgery, Duke University School of Medicine, Durham, NC.
Donna NiedzwieckiDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC.ORCID 0000-0002-3566-0450
Peter J AllenDepartment of Surgery, Duke University School of Medicine, Durham, NC.
Daniel P NussbaumDepartment of Surgery, Duke University School of Medicine, Durham, NC.ORCID 0000-0003-3070-6605
Zahra KabiriDepartment of Surgery, Duke University School of Medicine, Durham, NC.ORCID 0000-0002-2192-0725

Funding

Identifying Novel Intensity-Specific Regulators of RAS SignalingK22CA266753 · NCI · DUKE UNIVERSITY · PI KABIRI, ZAHRA · 2022 to 2024
$396k
NCI NIH HHS K22 CA266753
6 · The paper itself

Abstract

purposeAlthough MATERIALS AND

methodsWe used American Association for Cancer Research's GENIE Biopharma Consortium Pancreas v1.2 data set to test the association of codon-specific

resultsAmong 1,032 eligible patients, 949 (92%) exhibited mutant

conclusionThese findings demonstrated that codon-specific

Indexed as

Carcinoma, Pancreatic DuctalMutationPancreatic NeoplasmsProto-Oncogene Proteins p21(ras)AgedCodonFemaleHumansMaleMiddle AgedNeoplasm StagingPrognosisCodonKRAS protein, humanProto-Oncogene Proteins p21(ras)

Identifiers

PMID41712870
PMCPMC12931877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.