Evidence map›Paper›PMID 41712721›Full record

ArticleScience (New York, N.Y.)2026

The oncogenome of the domestic cat.

Bailey A Francis, Latasha Ludwig, Chang He, Melanie Dobromylskyj, Christof A Bertram, Heike Aupperle-Lellbach, Hannah Wong, Aiden P Foster, Mark J Arends, Alejandro Suárez-Bonnet and 17 more

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Bailey A Francis *Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, Cambridgeshire, UK.ORCID 0009-0008-9732-4058
Latasha Ludwig *Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.ORCID 0009-0009-8328-1031
Chang He *Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Melanie DobromylskyjFinn Pathologists, Weybread, Diss, Norfolk, UK.ORCID 0000-0002-0781-5726
Christof A BertramInstitute of Pathology, University of Veterinary Medicine Vienna, Wien, Austria.ORCID 0000-0002-2402-9997
Heike Aupperle-LellbachLaboklin GmbH & Co. KG, Laboratory for Clinical Diagnostics, Bad Kissingen, Germany.
Hannah WongDepartment of Veterinary Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.ORCID 0000-0002-9530-7106
Aiden P FosterBristol Veterinary School, University of Bristol, Langford, North Somerset, UK.ORCID 0000-0003-3808-8434
Mark J ArendsEdinburgh Pathology, Centre for Comparative Pathology, CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland.ORCID 0000-0002-6826-8770
Alejandro Suárez-BonnetDepartment of Pathobiology and Population Sciences, Royal Veterinary College, North Mymms, Hatfield, UK.ORCID 0000-0003-0296-5896
Simon L PriestnallDepartment of Pathobiology and Population Sciences, Royal Veterinary College, North Mymms, Hatfield, UK.ORCID 0000-0002-6027-1879
Laetitia TatierskyVETPATH Canada, Guelph, ON, Canada.ORCID 0009-0008-0373-4014
Fernanda Castillo-AlcalaTāwharau Ora-School of Veterinary Science, Massey University, Palmerston North, New Zealand.ORCID 0000-0002-0434-9096
Angie RuppSchool of Biodiversity, One Health & Veterinary Medicine, University of Glasgow, Glasgow, Scotland.ORCID 0000-0002-9413-0054
Arlene KhachadoorianDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.
Eda ParlakInstitute of Pathology, University of Veterinary Medicine Vienna, Wien, Austria.ORCID 0009-0001-7088-7116
Marine InglebertInstitute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Shevaniee UmamaheswaranWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, Cambridgeshire, UK.
Saamin CheemaWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, Cambridgeshire, UK.ORCID 0000-0002-5297-2042
Martin Del Castillo Velasco-HerreraWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, Cambridgeshire, UK.ORCID 0000-0001-5956-0211
Kim WongWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, Cambridgeshire, UK.ORCID 0000-0002-0984-1477
Ian C VermesWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, Cambridgeshire, UK.ORCID 0009-0000-3275-4892
Jamie BillingtonWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, Cambridgeshire, UK.
Sven RottenbergInstitute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.ORCID 0000-0003-2044-9844
Geoffrey A WoodDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.ORCID 0000-0003-1756-8607
David J AdamsWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, Cambridgeshire, UK.ORCID 0000-0001-9490-0306
Louise van der WeydenWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, Cambridgeshire, UK.ORCID 0000-0002-0645-1879

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is a common cause of morbidity and mortality in domestic cats. Because the mutational landscape of domestic cat tumors remains uncharacterized, we performed targeted sequencing of 493 feline tumor-normal tissue pairs from 13 tumor types, focusing on the feline orthologs of ~1000 human cancer genes.

Indexed as

Cat DiseasesNeoplasmsOncogenesAnimalsCatsDNA Copy Number Variationsfas ReceptorGerm-Line MutationHumansMutationProto-Oncogene Proteins c-mycPTEN PhosphohydrolaseTumor Suppressor Protein p53fas ReceptorProto-Oncogene Proteins c-mycPTEN PhosphohydrolaseTumor Suppressor Protein p53

Identifiers

PMID41712721
PMCPMC7618901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.