Evidence map›Paper›PMID 41712662›Full record

ArticleJournal of synchrotron radiation2026

Multifunctional bending magnet beamline with a capillary optic for X-ray fluorescence studies of metals in tissue sections.

Benjamin Roter, Andrew M Crawford, Qiaoling Jin, Arthur T Glowacki, Barry Lai, Fabricio S Marin, Evan Maxey, Xianbo Shi, Valeria C Culotta, Asia S Wildeman and 3 more

Abstract read
In one paragraph

Article in Journal of synchrotron radiation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Benjamin RoterApplied Physics Program, Northwestern University, Evanston, IL 60208, USA.
Andrew M CrawfordDepartment of Microbiology, Genetics and Immunology, Michigan State University, East Lansing, USA.ORCID 0000-0003-4641-7955
Qiaoling JinDepartment of Physics and Astronomy, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0002-3799-0613
Arthur T GlowackiX-ray Science Division, Advanced Photon Source, Argonne National Laboratory, Lemont, IL 60439, USA.
Barry LaiX-ray Science Division, Advanced Photon Source, Argonne National Laboratory, Lemont, IL 60439, USA.ORCID 0000-0002-6061-7155
Fabricio S MarinX-ray Science Division, Advanced Photon Source, Argonne National Laboratory, Lemont, IL 60439, USA.
Evan MaxeyX-ray Science Division, Advanced Photon Source, Argonne National Laboratory, Lemont, IL 60439, USA.ORCID 0000-0001-7519-5277
Xianbo ShiX-ray Science Division, Advanced Photon Source, Argonne National Laboratory, Lemont, IL 60439, USA.ORCID 0000-0002-1069-9981
Valeria C CulottaDepartment of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0000-0002-3213-1326
Asia S WildemanDepartment of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0009-0009-2082-9741
Naisargi K PatelDepartment of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0009-0003-5209-1928
Thomas V O'HalloranDepartment of Microbiology, Genetics and Immunology, Michigan State University, East Lansing, USA.ORCID 0000-0001-8732-5059
Chris JacobsenApplied Physics Program, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0001-8562-0353

Funding

TR&D Project 3: Photoacoustic Detection of Metal Fluxes at the Tissue LevelP41GM135018 · NIGMS · NORTHWESTERN UNIVERSITY · PI JACOBSEN, CHRIS JOHNSON, O'HALLORAN, THOMAS V · 2020 to 2024
$5.8M
National Institutes of Health, National Institute of General Medical Sciences P41GM135018National Institutes of Health, National Institute of General Medical Sciences R21AI54726National Institutes of Health, National Institute of General Medical Sciences R35GM136644NIGMS NIH HHS P41 GM135018
6 · The paper itself

Abstract

Scanning fluorescence X-ray microscopy lets one non-destructively and quantitatively map the distribution of most biologically important metals in cells and tissues. For studies on large-scale tissues and organs, a spatial resolution of several micrometres is often sufficient; in this case, bending magnets at synchrotron light sources provide abundant X-ray flux. We describe here the use of bending magnet beamline 8-BM-B at the Advanced Photon Source with two distinct microscopy stations: a pre-existing one with Kirkpatrick-Baez (KB) mirror optics for slightly higher throughput and the ability to accommodate samples tens of centimetres across, and a new prototype station with an axially symmetric, single-bounce, capillary optic with slightly less flux, but finer resolution at similar fluence per time. The KB station provides δ

Indexed as

MetalsSpectrometry, X-Ray EmissionSynchrotronsAnimalsEquipment DesignMicroscopy, FluorescenceMetalscapillary opticelemental analysisX-ray fluorescenceX-ray microscopy

Identifiers

PMID41712662
PMCPMC12948027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.