Evidence map›Paper›PMID 41712208›Full record

ArticleJAMA network open2026

Transplantation and Employment Earnings in Kidney Transplant Recipients.

Daisy Thomas, Calvin Diep, Ella Huszti, Juan Pablo Diaz-Martinez, Duminda Wijeysundera, Christopher D Witiw, Blayne A Sayed, Karim S Ladha

Abstract read
In one paragraph

Article in JAMA network open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daisy ThomasUniversity of Toronto, Toronto, Ontario, Canada.
Calvin DiepDepartment of Anesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada.
Ella HusztiBiostatistics Department, University Health Network, Toronto, Ontario, Canada.
Juan Pablo Diaz-MartinezBiostatistics Department, University Health Network, Toronto, Ontario, Canada.
Duminda WijeysunderaDepartment of Anesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada.
Christopher D WitiwLi Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada.
Blayne A SayedAjmera Transplant Centre, HBP & Multi-Organ Transplant Program, University Health Network, Toronto, Ontario, Canada.
Karim S LadhaDepartment of Anesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: Kidney transplantation improves survival and quality of life for individuals with end-stage kidney disease (ESKD). However, its effect on objective economic outcomes, such as employment income, remains insufficiently studied. Objective: To quantify changes in employment income before and after kidney transplantation in Canada using linked administrative health and tax data. Design, Setting, and Participants: This population-based cohort study included nationwide data from Canadian adults receiving a kidney transplant between 2007 and 2016. Data were from the Canadian Hospitalization and Taxation Database (C-HAT), which includes hospital discharge records and income tax data. Eligible adults were aged 30 to 62 years; exclusions included repeat or multiorgan transplants, residents of Quebec or territories, and individuals with incomplete tax data or those in the top or bottom 1% of income earners. Data analyses were conducted between June 2024 to October 2025. Exposure: Kidney transplant. Main Outcome and Measures: The primary outcome was annual employment income, derived from tax records for 3 years before and after transplant. Employment income was defined as the combined total of employment income, self-employment income, and other employment income, and adjusted to 2023 Canadian dollars using the Bank of Canada Consumer Price Index. A linear mixed-effects model was used to evaluate changes in income over time. Results: The final cohort included 3230 individuals (mean [SD] age, 47 [8.4] years), of whom 1120 (34.7%) were female and 2630 (81.4%) were aged 30 to 55 years. Pretransplant, income declined by $4293 per year (95% CI, -$4726 to -$3861 per year; P < .001); posttransplant, income increased by $1006 per year (95% CI, $406 to $1605; P = .001). Conclusions and Relevance: In this cohort study of 3230 kidney transplant recipients, kidney transplant was associated with a reversal of declining employment income, indicating meaningful economic recovery. These findings highlight the broader socioeconomic value of transplantation and may inform policies that support patients during pretransplant vulnerability and facilitate successful return to work.

Indexed as

EmploymentIncomeKidney Failure, ChronicKidney TransplantationTransplant RecipientsAdultCanadaCohort StudiesFemaleHumansMaleMiddle Aged

Identifiers

PMID41712208
PMCPMC12921529

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.