Evidence map›Paper›PMID 41712169›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2026

Immediate vs delayed left bundle branch block after transcatheter aortic valve replacement: incidence and risk factors for permanent pacemaker implantation.

Maayan Shrem, Oholi Tovia-Brodie, Moshe Rav Acha, Ziv Dadon, Maxime Zabern, Nimrod Perel, Danny Dvir, Michael Glikson, Yoav Michowitz

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Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Maayan Shrem *Cardiology Department, Jesselson Integrated Heart Center and Eisenberg R&D Authority, Shaare Zedek Medical Center, Jerusalem, Israel.
Oholi Tovia-Brodie *Cardiology Department, Jesselson Integrated Heart Center and Eisenberg R&D Authority, Shaare Zedek Medical Center, Jerusalem, Israel.
Moshe Rav AchaCardiology Department, Jesselson Integrated Heart Center and Eisenberg R&D Authority, Shaare Zedek Medical Center, Jerusalem, Israel.
Ziv DadonCardiology Department, Jesselson Integrated Heart Center and Eisenberg R&D Authority, Shaare Zedek Medical Center, Jerusalem, Israel.
Maxime ZabernDivision of Cardiovascular Medicine, Cardiac Electrophysiology Section, Shamir Medical Center, Be'er Yaakov, Israel.
Nimrod PerelCardiology Department, Jesselson Integrated Heart Center and Eisenberg R&D Authority, Shaare Zedek Medical Center, Jerusalem, Israel.
Danny DvirCardiology Department, Jesselson Integrated Heart Center and Eisenberg R&D Authority, Shaare Zedek Medical Center, Jerusalem, Israel.
Michael GliksonCardiology Department, Jesselson Integrated Heart Center and Eisenberg R&D Authority, Shaare Zedek Medical Center, Jerusalem, Israel.
Yoav MichowitzCardiology Department, Jesselson Integrated Heart Center and Eisenberg R&D Authority, Shaare Zedek Medical Center, Jerusalem, Israel. ymichowitz@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCharacteristics of patients with delayed compared to immediate new onset left bundle branch block (LBBB) after transcatheter aortic valve replacement (TAVR) are poorly defined.

objectivesTo describe the incidence and features of patients with delayed post TAVR LBBB as well as risk factors for permanent pacemaker implantation (PPI).

methods1469 consecutive TAVR patients were screened for the occurrence of new onset LBBB. ECG was performed within 1 week before the procedure, immediately post procedure, and daily thereafter until discharge. According to the immediate post TAVR ECG, patients were divided into 2 groups, immediate and delayed new onset LBBB. Both groups were followed for the occurrence of PPI and mortality.

resultsAmong patients who underwent TAVR, 296 (20.1%) developed new-onset LBBB, of whom, 282 were included the present study. LBBB occurred immediately after the procedure in 249 patients (88.3%) and was delayed in 33 patients (11.7%). Rates of both early PPI within 2 weeks as well as long term PPI and mortality were comparable between patients with immediate vs. delayed onset LBBB. In patients with immediate LBBB, QRS width correlated with a need for PPI, while in patients with delayed LBBB, PR prolongation of ≥ 115 ms differentiated between patients with and without PPI.

conclusionsThe appearance of new onset post TAVR LBBB may be delayed in ~ 12% of patients. These patients exhibit similar rates of PPI need and mortality; however different ECG parameters signify high risk for PPI need among these patients.

Indexed as

DelayedImmediateLeft Bunder Branch BlockPermanent pacemaker implantation (PPI)Transcatheter aortic valve replacement (TAVR)

Identifiers

PMID41712169

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.