Evidence map›Paper›PMID 41712087›Full record

ReviewCurrent gastroenterology reports2026

Dietary Therapy in Eosinophilic Esophagitis (EoE): A Practical Approach to Elimination.

Varan Perananthan, Diana L Snyder

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current gastroenterology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Varan PerananthanDivision of Gastroenterology and Hepatology, Mayo Clinic, 200 1 st St SW, Rochester, MN, 55905, US.
Diana L SnyderDivision of Gastroenterology and Hepatology, Mayo Clinic, 200 1 st St SW, Rochester, MN, 55905, US. Snyder.diana@mayo.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewTo provide an overview of current dietary elimination strategies for eosinophilic esophagitis (EoE) and propose a practical, patient-centered approach to guide dietary therapy. RECENT

findingsEmpiric elimination diets, including one- (1FED), two- (2FED), four- (4FED), and six-food (6FED) elimination strategies, have demonstrated varying efficacy, with broader elimination generally associated with higher histologic remission rates. Elemental diets remain the most effective but are often impractical. Allergy testing-directed diets have limited utility due to poor predictive accuracy. Recent data support a step-up approach—beginning with 1FED or 2FED and escalating as needed—as effective and better tolerated. Dietary elimination remains a cornerstone of EoE treatment. A stepwise, empiric approach that minimizes dietary burden while maintaining clinical efficacy is recommended. Personalizing diet therapy based on patient preferences and response can improve adherence and outcomes, and future research should continue refining strategies to balance efficacy, cost, and quality of life.

Indexed as

Elimination DietsEosinophilic EsophagitisFood HypersensitivityHumansDietary elimination therapyElemental dietEmpiric elimination dietsEosinophilic esophagitisFood allergens

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.