Evidence map›Paper›PMID 41712081›Full record

ArticleJournal of fluorescence2026

An ICT-FRET Fluorescent Probe Derived from Coumarin-Naphthalimide for Ratiometric Detection of Copper Ions.

Qiujuan Ma, Junhong Xu, Shuangyu Liu, Congjie Pan, Guojiang Mao, Ning Cui, Ruxue Xia

Abstract read
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In one paragraph

Article in Journal of fluorescence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qiujuan MaSchool of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, PR China. maqiujuan104@126.com.
Junhong XuDepartment of Electrical Engineering, North China University of Water Resources and Electric Power, Zhengzhou, 450011, PR China. xujunhong57@126.com.
Shuangyu LiuSchool of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, PR China.
Congjie PanSchool of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, PR China.
Guojiang MaoSchool of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, 453007, PR China.
Ning CuiSchool of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, PR China.
Ruxue XiaSchool of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, PR China.

Funding

Key Scientific and Technological Projects of Henan Province 252102321126the National Natural Science Foundation of China 21807027
6 · The paper itself

Abstract

This research presents a new ratiometric fluorescent probe designed for Cu²⁺ detection, utilizing a dual mechanism of intramolecular charge transfer (ICT) and fluorescence resonance energy transfer (FRET). In this probe, coumarin acts as the energy donor while naphthalimide serves as the acceptor, with a 2-picolinic ester moiety functioning as the Cu²⁺ binding site. In the absence of Cu²⁺, the 2-picolinic ester effectively suppresses electron transfer, inhibiting both ICT and FRET, resulting in strong blue fluorescence (λem = 478 nm) from the coumarin moiety. However, upon Cu²⁺ binding, the Cu

Indexed as

CopperCoumarinsFluorescence Resonance Energy TransferFluorescent DyesNaphthalimidesCell SurvivalFluorescent Chemosensor CompoundsHumansMolecular StructureCoppercoumarinCoumarinsFluorescent Chemosensor CompoundsFluorescent DyesNaphthalimidesCell imagingCopper ionsCoumarin-naphthalimideICT-FRETRatiometric fluorescent probe

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.