ArticleGeneral thoracic and cardiovascular surgery2026
Activated partial thromboplastin time is a potential risk factor for prolonged chest drain placement following surgery for primary spontaneous pneumothorax: a case-control study.
Article in General thoracic and cardiovascular surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
- Cautious interpretation of mildly prolonged aPTT as a predictor of prolonged chest drain placement after surgery for primary spontaneous pneumothorax: comments on Hatano et al.General thoracic and cardiovascular surgery · 2026Article
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5 authors.
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Abstract
objectivesPrimary spontaneous pneumothorax (PSP) is a condition that primarily affects young patients and has a high recurrence rate. While surgery is the treatment option associated with the lowest recurrence rate for PSP, some patients experience long-term chest drain placement due to prolonged air leak. Our study aimed to elucidate the relationship between coagulation abnormalities and prolonged postoperative air leak in PSP.
methodsPatients who underwent surgery for PSP were retrospectively reviewed. Patients were divided into the exploratory and the validation cohorts. From the exploratory cohort, patients with prolonged chest drain placement were identified as the air-leak prolonged (AL-P) group, and the Control group matched at a 1:4 ratio was selected using propensity score matching.
resultsIn the exploratory cohort, 15 patients were assigned to the AL-P group and 60 to the control group. Among the coagulation markers including prothrombin time, activated partial thromboplastin time (APTT) and platelet count, univariate analysis revealed a significantly prolonged APTT in the AL-P group (median 33 vs. 31 s, odds ratio 1.26, p = 0.006). Multivariate analysis identified prolonged APTT as an independent risk factor for prolonged chest drain placement. Receiver operating characteristic curve of APTT values for predicting the incidence of prolonged chest drain placement showed a cutoff of 31.5 s. In the validation cohort, patients with an APTT ≥ 31.5 s showed significantly longer chest drain placement (p = 0.03).
conclusionsOur study suggests a potential association between prolonged APTT and prolonged postoperative chest drain placement in patients with PSP.
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